Results 31 to 40 of about 1,085,849 (268)

Nanotechnology and Single Molecules

open access: yesChemPhysChem, 2004
For many years now, scientific and technological research has witnessed a dramatic increase of interest in studies of single molecules. A large number of ongoing projects are dealing with examinations of individual particles, and many of them have been funded by the Volkswagen Stiftung.
openaire   +3 more sources

The role of urinary pteridines as disease biomarkers

open access: yesPteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Live cell imaging of single RNA molecules with fluorogenic Mango II arrays

open access: yesNature Communications, 2020
Fluorogenic RNA aptamers have been used for RNA imaging, but folding and fluorescence stability often limited their use in high resolution applications.
Adam D. Cawte   +2 more
doaj   +1 more source

Surface Modification of Fluorescent Nanodiamonds for Biological Applications

open access: yesNanomaterials, 2021
Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility.
Hak-Sung Jung, Keir C. Neuman
doaj   +1 more source

Variations in Cell Surfaces of Estrogen Treated Breast Cancer Cells Detected by A Combined Instrument for Far-Field and Near-Field Microscopy

open access: yesAnalytical Cellular Pathology, 2002
The response of single breast cancer cells (cell line T‐47D) to 17β‐estradiol (E2) under different concentrations was studied by using an instrument that allows to combine far‐field light microscopy with high resolution scanning near‐field (AFM/SNOM ...
P. Perner   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Hierarchical mechanism of amino acid sensing by the T-box riboswitch

open access: yesNature Communications, 2018
Riboswitches on 5′ ends of mRNAs are important for bacterial gene regulation. Here the authors probe the mechanism of a tRNA aminoacylation sensing T-box riboswitch using single-molecule fluorescence microscopy to characterize dynamic solution ...
Krishna C. Suddala   +5 more
doaj   +1 more source

Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning

open access: yesNature Communications, 2020
Traces from single-molecule fluorescence microscopy (SMFM) experiments exhibit photophysical artifacts that typically make analysis time-consuming. Here, the authors have developed an easily accessible software, AutoSiM, for two distinct applications of ...
Jieming Li   +3 more
doaj   +1 more source

Dynamical conductance measurement of single molecular junctions with both high-speed and high-precision

open access: yesAIP Advances, 2022
Real-time and rapid monitoring of the electron transport in nanoscale structures is critical for understanding many fundamental phenomena. However, it is not possible to rapidly record the dynamical current that varied across several orders of magnitude ...
Haiyang Liu   +5 more
doaj   +1 more source

Dynamic Dissection of the Endocytosis of Porcine Epidemic Diarrhea Coronavirus Cooperatively Mediated by Clathrin and Caveolae as Visualized by Single-Virus Tracking

open access: yesmBio, 2021
Emerging and re-emerging coronaviruses cause serious human and animal epidemics worldwide. For many enveloped viruses, including coronavirus, it is evident that breaking the plasma membrane barrier is a pivotal and complex process, which contains ...
Yangyang Li   +5 more
doaj   +1 more source

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