Results 51 to 60 of about 5,030,666 (315)
Hierarchical mechanism of amino acid sensing by the T-box riboswitch
Nature Communications, 2018 Riboswitches on 5′ ends of mRNAs are important for bacterial gene regulation. Here the authors probe the mechanism of a tRNA aminoacylation sensing T-box riboswitch using single-molecule fluorescence microscopy to characterize dynamic solution ...
Krishna C. Suddala +5 more
doaj +1 more source
Nature Communications, 2020 Traces from single-molecule fluorescence microscopy (SMFM) experiments exhibit photophysical artifacts that typically make analysis time-consuming. Here, the authors have developed an easily accessible software, AutoSiM, for two distinct applications of ...
Jieming Li +3 more
doaj +1 more source
AIP Advances, 2022 Real-time and rapid monitoring of the electron transport in nanoscale structures is critical for understanding many fundamental phenomena. However, it is not possible to rapidly record the dynamical current that varied across several orders of magnitude ...
Haiyang Liu +5 more
doaj +1 more source
mBio, 2021 Emerging and re-emerging coronaviruses cause serious human and animal epidemics worldwide. For many enveloped viruses, including coronavirus, it is evident that breaking the plasma membrane barrier is a pivotal and complex process, which contains ...
Yangyang Li +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Confined environment facilitates stacked conformations in Holliday Junction
Chemical Physics Impact, 2023 Holliday Junction (HJ) is an important intermediate in homologous recombination and is involved in DNA break repair. It is a highly dynamic structure and transitions between two stacked isomers through an intermediate open conformer. However, the insight
Priya Agarwal +2 more
doaj +1 more source
Single molecule for the people [PDF]
Nature Cell Biology, 2008 I don't believe I have ever before read a microscopy textbook from cover to cover — but this one, reader, I did. Its two editors, Taekjip Ha and Paul Selvin, have set out to assemble a manual for cell biologists who want to extend their technical repertoires to include single-molecule techniques.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
A unifying model for microRNA-guided silencing of messenger RNAs
Nature CommunicationsSilencing by the miRNA-guided RNA induced silencing complex (miRISC) is dependent on Ago2-chaperoned base pairing between the miRNA 5′ seed (5′S) and a complementary sequence in the 3′ untranslated region of an mRNA.
Tanmay Chatterjee +4 more
doaj +1 more source
Lanthanide Single-Molecule Magnets [PDF]
Chemical Reviews, 2013 Researchers demonstrate that lanthanide single-molecule magnets (SMM) have the potential for new technological applications. SMMs can be considered as molecular analogues of classical bulk ferromagnets, making it possible to develop them for applications involving the storage and processing of digital information.
Woodruff, Daniel N. +2 more
openaire +3 more sources