Results 71 to 80 of about 5,030,666 (315)

Single-molecule peptide fingerprinting [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Protein sequencing remains a challenge for small samples. A sensitive sequencing technology will create the opportunity for single-cell proteomics and real-time screening for on-site medical diagnostics. To resolve protein identity, we previously developed a computational algorithm that analyzes the ordered sequence of ...
Jetty van Ginkel, Mike Filius, Malwina Szczepaniak, Pawel Tulinski, Anne S. Meyer, Chirlmin Joo   +5 more
openaire   +3 more sources

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Overview of Single-Molecule Speckle (SiMS) Microscopy and Its Electroporation-Based Version with Efficient Labeling and Improved Spatiotemporal Resolution

Sensors, 2017
Live-cell single-molecule imaging was introduced more than a decade ago, and has provided critical information on remodeling of the actin cytoskeleton, the motion of plasma membrane proteins, and dynamics of molecular motor proteins. Actin remodeling has
Sawako Yamashiro, Naoki Watanabe
doaj   +1 more source

Topoisomerase VI is a chirally-selective, preferential DNA decatenase

eLife, 2022
DNA topoisomerase VI (topo VI) is a type IIB DNA topoisomerase found predominantly in archaea and some bacteria, but also in plants and algae. Since its discovery, topo VI has been proposed to be a DNA decatenase; however, robust evidence and a mechanism
Shannon J McKie, Parth Rakesh Desai, Yeonee Seol, Adam MB Allen, Anthony Maxwell, Keir C Neuman   +5 more
doaj   +1 more source

Electrofluorochromism at the single-molecule level [PDF]

Science, 2018
Changing emission with charge states The fluorescence of electrochromic molecules changes with their charge state. Doppagne et al. studied the optical emission of single zinc-phthalocyanine molecules excited by electron injection from a scanning tunneling microscope tip. The molecules were adsorbed on salt
Benjamin Doppagne, Michael C. Chong, Hervé Bulou, Alex Boeglin, Fabrice Scheurer, Guillaume Schull   +5 more
openaire   +3 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Novel approaches for single molecule activation and detection

, 2014
How can we obtain tools able to process and exchange information at the molecular scale In order to do this, it is necessary to activate and detect single molecules under controlled conditions. This book focuses on the generation of biologically-inspired
Di Fabrizio, Enzo, Benfenati, Fabio, Torre, Vincent   +2 more
core   +1 more source

A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Nature Communications
Widespread manganese-sensing transcriptional riboswitches effect the dependable gene regulation needed for bacterial manganese homeostasis in changing environments.
Adrien Chauvier, Shiba S. Dandpat, Rosa Romero, Nils G. Walter   +3 more
doaj   +1 more source

Viruses and Tetraspanins: Lessons from Single Molecule Approaches

Viruses, 2014
Tetraspanins are four-span membrane proteins that are widely distributed in multi-cellular organisms and involved in several infectious diseases. They have the unique property to form a network of protein-protein interaction within the plasma membrane ...
Selma Dahmane, Eric Rubinstein, Pierre-Emmanuel Milhiet   +2 more
doaj   +1 more source