Results 81 to 90 of about 6,486,155 (264)
Development and mechanisms of photo-induced molecule junction device
NanophotonicsThe utilization of single molecule electronic devices represents a significant avenue toward advancing next-generation circuits. Recent investigations have notably augmented our understanding of the optoelectronic characteristics exhibited by diverse ...
Sun Xin +3 more
doaj +1 more source
Single-Particle Tracking Porcine Epidemic Diarrhea Virus Moving along Microtubules in Living Cells
Proceedings, 2020 Porcine epidemic diarrhea virus (PEDV), a member of the genus Alphacoronavirus, has caused severe damage to the swine industry. Although viruses are believed to hijack the microtubule-based transport system, the exact manner of PEDV moving along ...
Yangyang Li, Wei Hou, Jian Wang, Fei Liu
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Single-molecule and ensemble studies of DNA replication system [PDF]
, 2011 DNA replication is one the most important and complex systems in biology. In this dissertation, we first started from ensemble experiments, studying the clamp (PCNA) and the clamp loader (RFC) from the mesophilic archaeon Methanosarcina acetivorans, and ...
Liu, Cheng
core
Single-Molecule-Based Detection of Conserved Influenza A Virus RNA Promoter Using a Protein Nanopore
, 2019 Influenza A viruses (IAVs) cause annual epidemic and severe pandemic outbreaks worldwide and result in high mortality. Despite the importance of surveillance for preventing IAV infection, the existing techniques are inefficient for ultrasensitive ...
Sohee Oh (46468) +5 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
, 2022 Single-molecule processing scripts related to manuscript "MCM complexes are barriers that restrict cohesin-mediated loop ...
Duderstadt, Karl E., Scherr, Matthias J.
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Nature CommunicationsBiomolecular condensates, formed by liquid–liquid phase separation, coordinate key cellular activities. Recent work has revealed the role of sub-micron assemblies, or nanocondensates, in the organisation of a significant portion of the proteome. Here, we
Justin Houx +4 more
doaj +1 more source