Results 31 to 40 of about 1,193,038 (282)

Decoding the Structural Dynamics and Conformational Alternations of DNA Secondary Structures by Single-Molecule FRET Microspectroscopy

open access: yesFrontiers in Molecular Biosciences, 2021
In addition to the canonical double helix form, DNA is known to be extrapolated into several other secondary structural patterns involving themselves in inter- and intramolecular type hydrogen bonding. The secondary structures of nucleic acids go through
Debolina Bandyopadhyay   +3 more
doaj   +1 more source

Single-molecule peptide fingerprinting [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
Significance Protein sequencing remains a challenge for small samples. A sensitive sequencing technology will create the opportunity for single-cell proteomics and real-time screening for on-site medical diagnostics. To resolve protein identity, we previously developed a computational algorithm that analyzes the ordered sequence of ...
Jetty van Ginkel   +5 more
openaire   +3 more sources

Formation and Evolution of Single Molecule Junctions [PDF]

open access: yes, 2009
We analyze the formation and evolution statistics of single molecule junctions bonded to gold electrodes using amine, methyl sulfide and dimethyl phosphine link groups by measuring conductance as a function of junction elongation.
Hybertsen, M. S.   +7 more
core   +2 more sources

Sphingomyelin metabolism underlies Ras excitability for efficient cell migration and chemotaxis

open access: yesCell Structure and Function, 2023
In eukaryotic motile cells, the active Ras (Ras-GTP)-enriched domain is generated in an asymmetric manner on the cell membrane through the excitable dynamics of an intracellular signaling network.
Da Young Shin   +4 more
doaj   +1 more source

Thermopower of Single-Molecule Devices

open access: yes, 2004
We investigate the thermopower of single molecules weakly coupled to metallic leads. We model the molecule in terms of the relevant electronic orbitals coupled to phonons corresponding to both internal vibrations and to oscillations of the molecule as a ...
D. V. Averin   +8 more
core   +1 more source

Live cell imaging of single RNA molecules with fluorogenic Mango II arrays

open access: yesNature Communications, 2020
Fluorogenic RNA aptamers have been used for RNA imaging, but folding and fluorescence stability often limited their use in high resolution applications.
Adam D. Cawte   +2 more
doaj   +1 more source

Magnetoresistance through a single molecule

open access: yes, 2011
The use of single molecules to design electronic devices is an extremely challenging and fundamentally different approach to further downsizing electronic circuits. Two-terminal molecular devices such as diodes were first predicted [1] and, more recently,
A Arnold   +55 more
core   +1 more source

Quantum interference through gated single-molecule junctions [PDF]

open access: yes, 2012
We discuss the general form of the transmission spectrum through a molec- ular junction in terms of the Green function of the isolated molecule. By introducing a tight binding method, we are able to translate the Green func- tion properties into ...
Lovey, Daniel A., Romero, Rodolfo H.
core   +2 more sources

The role of urinary pteridines as disease biomarkers

open access: yesPteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Dynamic Dissection of the Endocytosis of Porcine Epidemic Diarrhea Coronavirus Cooperatively Mediated by Clathrin and Caveolae as Visualized by Single-Virus Tracking

open access: yesmBio, 2021
Emerging and re-emerging coronaviruses cause serious human and animal epidemics worldwide. For many enveloped viruses, including coronavirus, it is evident that breaking the plasma membrane barrier is a pivotal and complex process, which contains ...
Yangyang Li   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy