Results 121 to 130 of about 62,512 (285)

Conformational selection in protein binding and function

, 2014
Protein binding and function often involves conformational changes. Advanced NMR experiments indicate that these conformational changes can occur in the absence of ligand molecules (or with bound ligands), and that the ligands may 'select' protein ...
Paul, Fabian, Weikl, Thomas R.
core   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Probing Plasmons in Graphene by Resonance Energy Transfer

, 2011
We propose a novel method to probe electronic excitations in graphene by monitoring the fluorescence quenching of a semiconductor quantum dot (or a dye molecule) due to the resonance energy transfer to the graphene sheet.
Efimov, Anatoly, Velizhanin, Kirill A.
core   +1 more source

Applying Corrections in Single-Molecule FRET [PDF]

, 2016
AbstractSingle-molecule Förster resonance energy transfer (smFRET) experiments can detect the distance between a donor and an acceptor fluorophore on the 3-10nm scale. In ratiometric smFRET experiments, the FRET efficiency is estimated from the ratio of acceptor and total signal (donor + acceptor). An excitation scheme involving two alternating lasers (
openaire   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes

Nature Communications, 2018
Nucleosomes compact the genome and regulate access to specific DNA sequences. Here the authors employ single-molecule FRET studies to characterize nucleosome dynamics at different salt concentrations and dissect nucleosome disassembly into elementary ...
Alexander Gansen, Suren Felekyan, Ralf Kühnemuth, Kathrin Lehmann, Katalin Tóth, Claus A. M. Seidel, Jörg Langowski   +6 more
doaj   +1 more source

Different Fluorophore Labeling Strategies and Designs Affect Millisecond Kinetics of DNA Hairpins

Molecules, 2014
Changes in molecular conformations are one of the major driving forces of complex biological processes. Many studies based on single-molecule techniques have shed light on conformational dynamics and contributed to a better understanding of living matter.
Andreas Hartmann, Georg Krainer, Michael Schlierf   +2 more
doaj   +1 more source

iMAX FRET (Information Maximized FRET) for Multipoint Single-Molecule Structural Analysis

Nano Letters
Understanding the structure of biomolecules is vital for deciphering their roles in biological systems. Single-molecule techniques have emerged as alternatives to conventional ensemble structure analysis methods for uncovering new biology in molecular dynamics and interaction studies, yet only limited structural information could be obtained ...
Bhagyashree S. Joshi, Carlos de Lannoy, Mark R. Howarth, Sung Hyun Kim, Chirlmin Joo   +4 more
openaire   +3 more sources

Perspective: OLED Displays Singing with the Blues

Advanced Materials, EarlyView.
While blue pixels consume approximately 50% of the energy of OLED display front planes, in the 25 years since their invention, 100% internal efficiency triplet‐controlled phosphorescent OLEDs have not met the stability standards necessary for their adoption.
Stephen R. Forrest, Claire Arneson, Haonan Zhao   +2 more
wiley   +1 more source

Stiff to Soft: A Protein‐Based Buffer Layer for Improving the Long‐Term Performance of Microneedle Sensors

Advanced Materials, EarlyView.
To enhance stability and long‐term biocompatibility of wearable microneedle sensors, a crosslinking‐recombination bovine serum albumin material is used as a buffer layer coated on microneedle sensors. This coating layer possesses a unique stiff‐to‐soft transition function balancing the mechanical stiffness desired for puncturing and soft required for ...
Lihao Guo, Youbin Zheng, Shuxiang Xu, Bingbing Feng, Kan Wang, Rou Huang, Gandong Zhou, Chutong Liu, Rawan Omar, Danyao Qu, Jinbao Li, Min Zhang, Weiwei Wu, Guangjian Zhang, Lina Huang, Hossam Haick, Miaomiao Yuan   +16 more
wiley   +1 more source