Results 201 to 210 of about 5,805,397 (279)

Pretrained Deep Neural Network Kin-SiM for Single-Molecule FRET Trace Idealization. [PDF]

J Phys Chem B
Zhang L, Li J, Walter NG.
europepmc   +1 more source

Single-Molecule FRET and Tracking of Transfected Biomolecules in Living Cells

, 2023
Anandamurugan A, Eidloth A, Frank V, Wortmann P, Schrangl L, Lan C, Schütz GJ, Hugel T.   +7 more
europepmc   +1 more source

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

Advanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li, Honghua Hu, Xinli Jiang, Xuhuai Fu, Lin Hu, Qinghua Wu, Jiatong Chai, Diangeng Li, Jinhong Guo, Zhiqiang Li, Yi Li, Yirong Li   +11 more
wiley   +1 more source

Correction: RecA filament sliding on DNA facilitates homology search

eLife, 2013
Kaushik Ragunathan, Cheng Liu, Taekjip Ha   +2 more
doaj   +1 more source

Direct effect of membrane environment on the activation of mGluR2 revealed by single-molecule FRET. [PDF]

Structure
Banerjee C, Wey-Hung Liauw B, Vafabakhsh R.   +2 more
europepmc   +1 more source

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

Advanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang, Xingcan Pan, Yongling Ying, Ziqian Bai, Jingming Zhang, Zhuang Shao, Jialiang Qian, Hongwei Li, Ning Zhang, Fan Yang, Yuan Liu, Xing Yang   +11 more
wiley   +1 more source

Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET. [PDF]

Nucleic Acids Res
Groves D, Cunnison R, McMahon A, Fan H, Sharps J, Deng A, Keown JR, Fodor E, Robb NC.   +8 more
europepmc   +1 more source

An Epidermal Sweat Patch for Tracking Metabolite Levels and Correlation Analysis in Biofluids

Advanced Science, EarlyView.
This work presents an epidermal sweat patch for continuous glucose monitoring that validates a strong correlation between sweat, interstitial fluid and blood, enabling a reliable and non‐invasive platform for systemic health management. ABSTRACT Continuous, in situ monitoring of sweat biomarkers offers a promising approach for non‐invasive metabolic ...
Yao Chen, Xinhao Wan, Haoxin Fan, Hengwei Lou, Jialu Wang, Jie Gao, Dan Wen   +6 more
wiley   +1 more source

Accounting for Fast vs Slow Exchange in Single Molecule FRET Experiments Reveals Hidden Conformational States. [PDF]

J Chem Theory Comput
Miller JJ, Mallimadugula UL, Zimmerman MI, Stuchell-Brereton MD, Soranno A, Bowman GR.   +5 more
europepmc   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source