Results 1 to 10 of about 260,270 (219)

Genetic epidemiology of single-nucleotide polymorphisms [PDF]

Proceedings of the National Academy of Sciences, 1999
On the causal hypothesis, most genetic determinants of disease are single-nucleotide polymorphisms (SNPs) that are likely to be selected as markers for positional cloning. On the proximity hypothesis, most disease determinants will not be included among markers but may be detected through linkage disequilibrium with other SNPs.
Andrew Collins, Christine Lonjou, Newton E. Morton   +2 more
openalex   +5 more sources

Electrophoretic Detection of Single-Nucleotide Polymorphisms [PDF]

BioTechniques, 2000
Single-nucleotide polymorphisms (SNPs) represent the most prevalent class of genetic markers available for linkage disequilibrium or cladistic analyses. PCR primers may be labeled with fluorescent dyes and used to rapidly and accurately differentiate among alleles that are defined by a single-nucleotide differences.
Deven R. See, Vladimir Kanazin, Hope Talbert, Tom Blake   +3 more
openalex   +5 more sources

Detection of Single-Nucleotide Polymorphism

BioTechniques, 1998
Weikuan Gu, Gustavo D. Aguirre, Kunal Ray   +2 more
doaj   +4 more sources

Flow Cytometric Platform for High-Throughput Single Nucleotide Polymorphism Analysis [PDF]

BioTechniques, 2001
We have developed a rapid, cost-effective, high-throughput readout for single nucleotide polymorphism (SNP) genotyping using flow cytometric analysis performed on a Luminex™ 100 flow cytometer.
J.D. Taylor, D. Briley, Q. Nguyen, K. Long, M.A. Iannone, M.-S. Li, F. Ye, A. Afshari, E. Lai, M. Wagner, J. Chen, M.P. Weiner   +11 more
doaj   +2 more sources

TMPRSS2 gene, single nucleotide polymorphism rs8134378, single nucleotide polymorphism rs12329760.

Syrian Journal for Science and Innovation, 2023
Since the spread of the COVID-19 pandemic, there has been a variation in the prevalence rates of the coronavirus that causes the disease, the distribution of moderate and severe symptoms, and death rates, among different populations.
Majd Aljamali , Lama Youssef
doaj   +1 more source

Single-Nucleotide Polymorphisms in Soybean [PDF]

Genetics, 2003
Abstract Single-nucleotide polymorphisms (SNPs) provide an abundant source of DNA polymorphisms in a number of eukaryotic species. Information on the frequency, nature, and distribution of SNPs in plant genomes is limited. Thus, our objectives were (1) to determine SNP frequency in coding and noncoding soybean (Glycine max L.
Perry B. Cregan, David L. Hyten, Qijian Song, Qijian Song, S. M. Hyatt, Lakshmi K. Matukumalli, Lakshmi K. Matukumalli, Edward W. Fickus, Youlin Zhu, Youlin Zhu, Nevin D. Young, Dirk Grimm, C.P. Van Tassell   +12 more
openaire   +3 more sources

Detection of Single Nucleotide Polymorphisms [PDF]

Current Issues in Molecular Biology, 2003
Single nucleotide polymorphism (SNP) detection technologies are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences. SNP detection technologies have evolved from labor intensive, time consuming, and expensive processes to some of the most highly automated, efficient, and relatively inexpensive ...
Kwok, Pui-Yan, Chen, Xiangning
openaire   +3 more sources

Predicting late-stage age-related macular degeneration by integrating marginally weak SNPs in GWA studies

Frontiers in Genetics, 2023
Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease and the leading cause of blindness in developed countries.
Xueping Zhou, Jipeng Zhang, Ying Ding, Heng Huang, Yanming Li, Wei Chen   +5 more
doaj   +1 more source

Recent Progress in Single-Nucleotide Polymorphism Biosensors

Biosensors, 2023
Single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in the human genome, are the main cause of individual differences. Furthermore, such attractive genetic markers are emerging as important hallmarks in clinical diagnosis ...
Kaimin Wu, Feizhi Kong, Jingjing Zhang, Ying Tang, Yao Chen, Long Chao, Libo Nie, Zhao Huang   +7 more
doaj   +1 more source

Analysis of GLT6D1 and CDKN2BAS gene polymorphisms in Brazilian patients with advanced periodontitis

Brazilian Oral Research, 2022
Gene polymorphisms can predispose to periodontal disease, as demonstrated by the well-documented association between aggressive periodontitis and single nucleotide polymorphisms (SNPs) such as rs153745 in the GLT6D1 gene and rs3217992 in the CDKN2BAS ...
Richelle Soares RODRIGUES, Rodrigo RÊGO, Raquel Mantuaneli Scarel CAMINAGA, Jéssica Marina GOVEIA, Virginia Régia Souza SILVEIRA   +4 more
doaj   +1 more source