Results 251 to 260 of about 724,526 (380)

SBE-TAGS: An array-based method for efficient single-nucleotide polymorphism genotyping

, 2000
Joel N. Hirschhorn, Pamela Sklar, Kerstin Lindblad‐Toh, Yin-Mei Lim, Melisa Ruiz‐Gutierrez, Stacey Bolk, Bradley W. Langhorst, S. F. Schaffner, Ellen Winchester, Eric S. Lander   +9 more
openalex   +1 more source

Chromosomal localization, structure, single-nucleotide polymorphisms, and expression of the human H-protein gene of the glycine cleavage system (GCSH), a candidate gene for nonketotic hyperglycinemia [PDF]

, 2001
Shuichi KURE, Kazuhiro Kojima, T Kudo, K. Kanno, Yoshitsugu Aoki, Yoichi Suzuki, Toshikatsu Shinka, Yasushi Sakata, K. Narisawa, Yoichi Matsubara   +9 more
openalex   +1 more source

Lamivudine and tenofovir pharmacokinetic variability in people with HIV in Papua New Guinea

British Journal of Clinical Pharmacology, EarlyView.
Aims Demographics and kidney function contribute to variability in lamivudine and tenofovir drug concentrations. The aim was to assess, for the first time, the pharmacokinetic variability of lamivudine and tenofovir in Papua New Guinean (PNG) HIV/AIDS patients.
Natália Bordin Andriguetti, Daniel Thomas Barratt, Joseph Tucci, Paul Pumuye, Andrew Alexander Somogyi   +4 more
wiley   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Single nucleotide polymorphism and expression of P16 gene as a potential biomarker for oral and pre-oral cancer. [PDF]

Discov Oncol
Nigam K, Verma Y, Kulshrestha MR, Singh A, Sanyal S.   +4 more
europepmc   +1 more source

Catalog of 46 single-nucleotide polymorphisms (SNPs) in the microsomal glutathione S-transferase 1 (MGST1) gene [PDF]

, 2001
Aritoshi Iida, S. Saito, Akihiro Sekine, S. Harigae, Satoshi Osawa, C. Mishima, Kazuhiro Kondo, Y. Kitamura, Yoshimasa Nakamura   +8 more
openalex   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Single nucleotide polymorphisms of the resistin (RSTN) gene [PDF]

, 2001
Henian Cao, Robert A. Hegele
openalex   +1 more source

Discovery and development of exome-based, co-dominant single nucleotide polymorphism markers in hexaploid wheat (Triticum aestivum L.).

Plant Biotechnology Journal, 2013
A. Allen, G. Barker, P. Wilkinson, A. Burridge, M. Winfield, J. Coghill, C. Uauy, S. Griffiths, P. Jack, S. Berry, P. Werner, J. Melichar, Jane McDougall, R. Gwilliam, P. Robinson, K. Edwards   +15 more
semanticscholar   +1 more source

Zebrafish: A Versatile and Powerful Model for Biomedical Research

BioEssays, EarlyView.
Zebrafish are vital for advancing precision medicine, offering a genetically tractable and optically transparent vertebrate model with strong genetic homology to humans. They enable rapid and cost‐effective disease modeling and drug discovery, accelerating insights into cardiovascular, neurological, metabolic, and oncological disorders through gene ...
Sundus Siddiqui, Hiba Siddiqui, Emna Riguene, Michail Nomikos   +3 more
wiley   +1 more source