Results 81 to 90 of about 1,316,697 (275)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Impact of ionization potential depression on single particle imaging

Physical Review Research
Ultraintense and ultrashort x-ray free-electron laser (XFEL) pulses promise single particle imaging (SPI) via enabling collection of diffraction data for nanocrystals, or nano-size nonperiodic objects before the destruction of the sample. Photoionization
Sourav Banerjee, Zoltan Jurek, Rui Jin, Sang-Kil Son, Robin Santra   +4 more
doaj   +1 more source

Fluorescent silica manoparticles with well-separated intensity distributions from batch reactions [PDF]

, 2018
Silica chemistry provides pathways to uniquely tunable nanoparticle platforms for biological imaging. It has been a long-standing problem to synthesize fluorescent silica nanoparticles (SNPs) in batch reactions with high and low fluorescence intensity ...
Andrievsky, Alexander, Aubert, Tangi, Kao, Teresa, Kohle, Ferdinand, Ma, Kai, Wiesner, Ulrich   +5 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Nano-scale measurement of biomolecules by optical microscopy and semiconductor nanoparticles

Frontiers in Physiology, 2014
Over the past decade, great developments in optical microscopy have made this technology increasingly compatible with biological studies. Fluorescence microscopy has especially contributed to investigating the dynamic behaviors of live specimens and can ...
Taro eIchimura, Takashi eJin, Takashi eJin, Takashi eJin, Hideaki eFujita, Hideaki eFujita, Hideo eHiguchi, Tomonobu M Watanabe, Tomonobu M Watanabe, Tomonobu M Watanabe   +9 more
doaj   +1 more source

Direct probing of single-molecule chemiluminescent reaction dynamics under catalytic conditions in solution

Nature Communications, 2023
Chemical reaction kinetics can be evaluated by probing dynamic changes of chemical substrates or physical phenomena accompanied during the reaction process.
Ziqing Zhang, Jinrun Dong, Yibo Yang, Yuan Zhou, Yuang Chen, Yang Xu, Jiandong Feng   +6 more
doaj   +1 more source

Denoising and covariance estimation of single particle cryo-EM images [PDF]

Journal of Structural Biology, 2016
Revision for ...
Bhamre, Tejal, Zhang, Teng, Singer, Amit
openaire   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Electrospray sample injection for single-particle imaging with x-ray lasers

Science Advances, 2018
Electrospray contaminant-free delivery of proteins to x-ray laser heralds the start of single-protein x-ray diffractive imaging. The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers. Despite encouraging results on
J. Bielecki, M. Hantke, B. Daurer, Hemanth K N Reddy, D. Hasse, D. Larsson, Laura H. Gunn, M. Svenda, A. Munke, J. Sellberg, L. Flueckiger, Alberto Pietrini, Carl Nettelblad, I. Lundholm, G. Carlsson, Kenta Okamoto, N. Tîmneanu, D. Westphal, O. Kulyk, A. Higashiura, Gijs van der Schot, N. D. Loh, Taylor E. Wysong, Christoph Bostedt, T. Gorkhover, B. Iwan, M. Seibert, T. Osipov, P. Walter, P. Hart, M. Bucher, A. Ulmer, D. Ray, G. Carini, Kevin Ferguson, I. Andersson, J. Andreasson, Janos Hajdu, F. Maia   +38 more
semanticscholar   +1 more source

Impact of ultrafast electronic damage in single particle x-ray imaging experiments

, 2012
In single particle coherent x-ray diffraction imaging experiments, performed at x-ray free-electron lasers (XFELs), samples are exposed to intense x-ray pulses to obtain single-shot diffraction patterns.
E. Weckert, F. Herman, I. A. Vartanyants, J. Als-Nielsen, L. Mandel, M. M. Woolfson, N. M. Kabachnik, U. Lorenz   +7 more
core   +1 more source