Results 201 to 210 of about 12,921,630 (316)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Study of gene expression dynamics at Single Cell resolution during neurodifferentiation

reservedLo sviluppo embrionale umano è un processo complesso durante il quale lo zigote cresce e si specializza per formare tutte le cellule presenti nel corpo umano.
DE BENI, FRANCESCA
core  

Single‐cell genomics [PDF]

Environmental Microbiology, 2007
openaire   +2 more sources

Rapid and robust diagnosis of bloodstream infections by single-cell analysis. [PDF]

Sci Adv
Chin SM, Epiphaniou E, Kovtunov E, Mach KE, Liao JC, Bobenchik AM, Yang S, Wong PK.   +7 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Author Correction: Histone H2A monoubiquitination marks are targeted to specific sites by cohesin subunits in Arabidopsis

Nature Communications
Yu Zhang, Min Ma, Meng Liu, Aiqing Sun, Xiaoyun Zheng, Kunpeng Liu, Chunmei Yin, Chuanshun Li, Cizhong Jiang, Xiaoyu Tu, Yuda Fang   +10 more
doaj   +1 more source

Single-cell ionomes of terrestrial cryosphere algae. [PDF]

Commun Earth Environ
Oliveira SR, Feord HK, Lopes Júnior CA, Sven Peters R, Benning LG, Meermann B.   +5 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial Intelligence-Empowered Single-Cell Phenotyping for Rapid, Automated Pathogen Diagnostics. [PDF]

Adv Sci (Weinh)
Khadka S, Raahat B, Tragoudas S, Li H.
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source