Results 61 to 70 of about 7,341,382 (291)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

PGF2α levels in Day 8 blood plasma are increased by the presence of one or more embryos in the uterus

Animal, 2015
In cattle, the detection of very early endometrial responses is considered to be hampered by the presence of only a single embryo. Therefore, we have previously developed a model of multiple embryo transfer to circumvent this hindrance.
E. Gomez, D. Martin, S. Carrocera, M. Muñoz   +3 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Effect of frozen-thawed embryo transfer with a poor-quality embryo and a good-quality embryo on pregnancy and neonatal outcomes

Reproductive Biology and Endocrinology
Background To evaluate the impact of embryo quality and quantity, specifically a poor quality embryo (PQE) in combination with a good quality embryo (GQE), by double embryo transfer (DET) on the live birth rate (LBR) and neonatal outcomes in patients ...
Cheng Zeng, Rui-Hui Lu, Xin Li, Sheng Wang, Yan-Rong Kuai, Qing Xue   +5 more
doaj   +1 more source

Case Report: Monochorionic triamniotic triplet pregnancy following single vitrified-warmed blastocyst transfer

Frontiers in Reproductive Health
Monochorionic triamniotic triplet pregnancy following single embryo transfer is an exceptionally rare outcome of assisted reproductive technology. We report a monochorionic triamniotic triplet pregnancy following transfer of a single vitrified-warmed ...
Artem A. Aksenenko, Tatyana A. Kodyleva, Polina O. Patskova, Alla A. Gavisova, Gennadiy T. Sukhikh   +4 more
doaj   +1 more source

Minimal ovarian stimulation combined with elective single embryo transfer policy: age-specific results of a large, single-centre, Japanese cohort

Reproductive Biology and Endocrinology, 2012
Background The two main complications associated with the use of assisted reproduction techniques, ovarian hyperstimulation syndrome and multiple pregnancies, could be eliminated by milder ovarian stimulation protocols and the increased use of a single ...
Kato Keiichi, Takehara Yuji, Segawa Tomoya, Kawachiya Satoshi, Okuno Takashi, Kobayashi Tamotsu, Bodri Daniel, Kato Osamu   +7 more
doaj   +1 more source

Prolonging the time of progesterone supplementation to improve the pregnancy outcomes of single day 6 blastocyst transfer in frozen-thawed cycles: study protocol for a randomized controlled trial

Trials, 2022
Background Infertility is one of the most important and underappreciated reproductive health problems in developing countries. Currently, in vitro fertilization and embryo transfer is the most effective treatment strategy for infertility.
Manlin Xu, Yuan Yan, Xiaoyue Shen, Haixiang Sun, Guijun Yan, Na Kong, Yue Jiang   +6 more
doaj   +1 more source

Clinical aspects of embryo implantation: from the perspective of tissue perfusion. [PDF]

, 2006
Hypothesis: Pelvic perfusion is the pivotal factor for the outcome of in vitro fertilisation (IVF) treatment once clinical and embryological variables are controlled for their effect.;Demonstration of Hypothesis: In a series of three studies, the ...
Ozturk, O., Ozturk, Ozkan
core  

Elective single embryo transfer- the power of one

, 2017
Despite the highest historical live birth success rates for couples undergoing in vitro fertilization (IVF), there has been an epidemic of iatrogenic twin and higher order gestation conceived from this treatment. Continued improvement in cryopreservation
Csokmay, John M., Lee, Amy M., Connell, Matthew T., Styer, Aaron   +3 more
core   +1 more source