Results 31 to 40 of about 10,451,032 (401)

Improved maize reference genome with single-molecule technologies

open access: yesNature, 2017
Complete and accurate reference genomes and annotations provide fundamental tools for characterization of genetic and functional variation. These resources facilitate the determination of biological processes and support translation of research findings ...
Yinping Jiao   +27 more
semanticscholar   +1 more source

An intermolecular FRET sensor detects the dynamics of T cell receptor clustering

open access: yesNature Communications, 2017
Cellular signalling is often facilitated by membrane protein clustering, but detection of protein clustering at high spatiotemporal resolution is challenging.
Yuanqing Ma   +8 more
doaj   +1 more source

Resolving Subcellular miRNA Trafficking and Turnover at Single-Molecule Resolution

open access: yesCell Reports, 2017
Summary: Regulation of microRNA (miRNA) localization and stability is critical for their extensive cytoplasmic RNA silencing activity and emerging nuclear functions.
Sethuramasundaram Pitchiaya   +4 more
doaj   +1 more source

Coupling single molecule magnets to quantum circuits [PDF]

open access: yes, 2013
In this work we study theoretically the coupling of single molecule magnets (SMMs) to a variety of quantum circuits, including microwave resonators with and without constrictions and flux qubits.
García-Ripoll, J.   +5 more
core   +3 more sources

Single-molecule detection on a portable 3D-printed microscope

open access: yesNature Communications, 2019
Single-molecule in vitro assays require dedicated confocal microscopes equipped with fluorescence correlation spectroscopy (FCS) modules. Here the authors present a compact, cheap and open-source 3D-printed confocal microscope for single photon counting ...
James W. P. Brown   +7 more
doaj   +1 more source

Protocol to generate fast-dissociating recombinant antibody fragments for multiplexed super-resolution microscopy

open access: yesSTAR Protocols, 2023
Summary: Multiplexed high-density label super-resolution microscopy image reconstruction by integrating exchangeable single-molecule localization (IRIS) enables elucidating fine structures and molecular distribution in cells and tissues.
Qianli Zhang   +2 more
doaj   +1 more source

Advances and challenges in single-molecule electron transport [PDF]

open access: yesReviews of Modern Physics, 2019
Electronic transport properties for single-molecule junctions have been widely measured by several techniques, including mechanically controllable break junctions, electromigration break junctions or by means of scanning tunneling microscopes.
F. Evers   +3 more
semanticscholar   +1 more source

DNA double helices for single molecule electronics [PDF]

open access: yes, 2007
The combination of self-assembly and electronic properties as well as its true nanoscale dimensions make DNA a promising candidate for a building block of single molecule electronics.
A. V. Malyshev   +3 more
core   +2 more sources

Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics

open access: yesNucleic Acids Research, 2018
Short read massive parallel sequencing has emerged as a standard diagnostic tool in the medical setting. However, short read technologies have inherent limitations such as GC bias, difficulties mapping to repetitive elements, trouble discriminating ...
S. Ardui   +3 more
semanticscholar   +1 more source

Single-molecule spectroscopy near structured dielectrics [PDF]

open access: yes, 1998
We present an analytical approach to the calculation of the linewidth and lineshift of an atom or molecule in the near field of a structured dielectric surface.
Agarwal   +39 more
core   +3 more sources

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