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BioNEMS: Nanomechanical Systems for Single-Molecule Biophysics
2007© 2007 Springer. We gratefully acknowledge interactions and work with the Caltech BioNEMS collective, spanning the Roukes, Fraser, Cross, and Phillips research groups. We are also grateful for support from DARPA/DSO SIMBIOSYS, via AFOSR grant number F49620-02-1-0085. M.P. thanks the Wellcome Foundation "Interfaces" program for additional support.
Arlett, J. L. +5 more
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Nanoelectronics, sensors and single molecule biophysics
Journal of Physics: Condensed Matter, 2012This special section of Journal of Physics: Condensed Matter (JPCM) is dedicated to Professor Stuart M Lindsay on the occasion of his 60th birthday and in recognition of his outstanding contributions to multiple research areas, including light scattering spectroscopy, scanning probe microscopy, biophysics, solid–liquid interfaces and molecular and ...
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Single-Molecule Biophysics with Optofluidic Trapping
Frontiers in Optics 2011/Laser Science XXVII, 2011Abstract (35 Word Limit) I will present our recent work on the optical trapping and manipulation of single molecules and nanomaterials using the near-field of integrated photonic devices.
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Single-Molecule Biophysical Imaging, Superresolution, and Trapping
Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, 2009Single-molecule emitters provide nanoscale light sources yielding unprecedented new information about biological systems. Novel methods and molecules, including superresolution imaging in three dimensions and anti-Brownian electrokinetic trapping of single biomolecules in solution, will be reviewed.
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Solid-state electronics and single-molecule biophysics
70th Device Research Conference, 2012Biomolecular systems are traditionally studied using ensemble measurements and fluorescence-based detection. Among the most common in vitro applications are DNA microarrays to identify target gene expression profiles [1] and enzyme-linked immunosorbent assays (ELISA) to identify proteins [2].
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Exploring Biophysics at the Membrane with Single-Molecule TIRF Microscopy
Cellular functions result from the action of heteromeric protein machines that typically exhibit greater utility and dynamism than the sum of their parts. Therefore, the structural composition of these multimeric machines must be determined to delineate their functional attributes, including how information is transduced between the extracellular and ...R Charles, Kissell +3 more
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