Results 201 to 210 of about 512,200 (259)

Single-Nucleotide Polymorphism Mapping

2006
Single-nucleotide polymorphism (SNP) mapping is the easiest and most reliable way to map genes in Caenorhabditis elegans. SNPs are extremely dense and usually have no associated phenotype, making them ideal markers for mapping. SNP mapping has three steps.
M. Wayne Davis, Marc Hammarlund
openaire   +3 more sources

Single-Nucleotide Polymorphisms

2006
The identification of DNA variation or gene mutations, which contributes to or determines a disease, has been a major research focus, as it describes the underlying inherited disease components. With the human genome being sequenced, the reference sequence is now at hand, facilitating the systematic identification of DNA variation and its subsequent ...
Ulrich Broeckel, Martin J. Hessner
openaire   +2 more sources

Single Nucleotide Polymorphisms and Pharmacogenomics

2021
Pharmaco-genomics determines the individual genetic mechanism for drug response and has the ability to transform tailored medication into clinical practice. A huge number of individuals die every year from adverse drug response since each person reacts differently to similar drug.
Sabhiya Majid, Hilal Ahmad Wani, Iyman Rasool, Muneeb U. Rehman, Muneeb U. Rehman, Azher Arafah, Samia Rashid, Shafat Ali, Shafat Ali, Shabhat Rasool   +9 more
openaire   +2 more sources

Single nucleotide polymorphisms in breast cancer

Oncology Reports, 2004
A limited number of genes have been identified that explain heritable risks of breast cancer (BC). We searched for low-penetrant genes in an association study using two populations: 223 Finnish unselected patients and 172 Polish familial cases, both with locally collected healthy controls.
Ewa Grzybowska, Fabiola Festa, Zhenzhong Zhang, Zhenzhong Zhang, Jolanta Pamula, Rajesh Kumar, Rajesh Kumar, Somali Sanyal, Helena Zientek, Sabrina Angelini, Kari Hemminki, Asta Försti, Wioletta Pekala   +12 more
openaire   +4 more sources

Single Nucleotide Polymorphisms (SNPs)

2014
Single nucleotide polymorphisms (SNPs) have been suggested as a useful tool for dissecting various human complex disorders, classically at a small scale and recently at large genome-wide levels. The advent of new technologies, including chip-based genotyping as well as high-throughput next generation sequencing, has opened new avenues for SNPs to be ...
Batra, Jyotsna, Srinivasan, Srilakshmi, Clements, Judith   +2 more
openaire   +3 more sources

Single Nucleotide Polymorphism

, 2014
Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations in the genome. They have been studied extensively in the last decade with various purposes in mind.
C. Børsting, V. Pereira, J. D. Andersen, Niels Morling   +3 more
semanticscholar   +1 more source

Cytokine Single Nucleotide Polymorphisms in Iran

Journal of Interferon & Cytokine Research, 2006
Overall expression and secretion of cytokines are dependent on genetic nucleotide variations within or adjacent to regulatory regions of cytokine genes. This study allows the comparison of the prevalence of particular genetic markers. In 40 Iranian healthy subjects, cytokine single nucleotide polymorphisms (SNPs) were used to determine allelic and ...
Davood Omrani, Mortaza Bagheri, Isa Abdi-Rad   +2 more
openaire   +3 more sources

Genotyping of Single Nucleotide Polymorphisms

2015
Single nucleotide polymorphisms (SNPs) are the most abundant DNA variations in human genome. Numerous reports have indicated that SNPs are closely associated with diseases such as cardiovascular diseases, different types of cancer, and other genetic diseases.
Tian Ye, Ran Tong, Zhiqiang Gao
openaire   +2 more sources

Single-Nucleotide Polymorphism Analysis by Pyrosequencing

Analytical Biochemistry, 2000
There is a growing demand for high-throughput methods for analysis of single-nucleotide polymorphic (SNP) positions. Here, we have evaluated a novel sequencing approach, pyrosequencing, for such purposes. Pyrosequencing is a sequencing-by-synthesis method in which a cascade of enzymatic reactions yields detectable light, which is proportional to ...
Baback Gharizadeh, Anna C. Gustafsson, Pål Nyrén, Afshin Ahmadian, Joakim Lundeberg, Mathias Uhlén, Fredrik Sterky   +6 more
openaire   +3 more sources

Single nucleotide polymorphism hunting in cyberspace

Human Mutation, 1998
Large-scale sequencing of human cDNA and genomic DNA libraries has produced a large collection of sequence data in public databases. To date, >900,000 human expressed sequence tag (EST) sequences and >80,000,000 bases of genomic DNA sequence have been deposited in Genbank.
Pui-Yan Kwok, LaDeana W. Hillier, Zhijie Gu   +2 more
openaire   +3 more sources