Results 201 to 210 of about 479,118 (340)

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study [PDF]

, 2009
Mari Levula, Niku Airla, Niku Oksala, Jussi Hernesniemi, Markku Pelto‐Huikko, Juha‐Pekka Salenius, Rainer Zeitlin, Otso Järvinen, Ari‐Pekka J. Huovila, Seppo T. Nikkari, Olli Jaakkola, Erkki Ilveskoski, Jussi Mikkelsson, Markus Perola, Reijo Laaksonen, Leena Kytömäki, Juhani T. Soini, Mika Kähönen, Jyrki Parkkinen, Pekka J. Karhunen, Terho Lehtimäki   +20 more
openalex   +1 more source

Supplementary Table 1 from Genome-Wide Copy Number Analysis in Esophageal Adenocarcinoma Using High-Density Single-Nucleotide Polymorphism Arrays

, 2023
Derek J. Nancarrow, Herlina Y. Handoko, B. Mark Smithers, D. C. Gotley, Paul A. Drew, David I. Watson, Andrew D. Clouston, Nicholas K. Hayward, David C. Whiteman   +8 more
openalex   +1 more source

Unraveling Novel Genetic Determinants of Thiopurine Response Via TWAS

Clinical Pharmacology &Therapeutics, EarlyView.
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Thiopurines such as 6‐mercaptopurine (6MP) are essential in ALL maintenance therapy. However, dose‐limiting toxicities can significantly disrupt treatment. While genetic variants in TPMT and NUDT15 are known to affect thiopurine response, many patients with normal function ...
Carlotta Bidoli, Wenjian Yang, Seth E. Karol, Marianna Lucafò, Gabriele Stocco, Jun J. Yang   +5 more
wiley   +1 more source

Exploring the presence of the GPR126 single nucleotide polymorphism (rs536714306) in periodontal patients of European ancestry. [PDF]

BMC Res Notes
Chatzopoulou E, Fanourakis G, Papanikolaou N, Chatzistamou I, Dereka X, Vastardis H.   +5 more
europepmc   +1 more source

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes [PDF]

, 2015
Kathy L. McGraw, Thomas Cluzeau, David A. Sallman, Ashley A. Basiorka, Brittany Irvine, Ling Zhang, Pearlie K. Epling‐Burnette, Dana E. Rollison, Mar Mallo, Lubomir Sokol, Françesc Solé, Jaroslaw P. Maciejewski, Alan F. List   +12 more
openalex   +1 more source

GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics enables the personalization of drug therapy by linking genetic variations to differences in drug metabolism, efficacy, and risk of adverse reactions. Genetic polymorphisms within cytochrome P450 (CYP) genes significantly affect enzyme activity, influencing drug plasma levels, responses, and safety.
Alex J. Coulter, Megana Thamilselvan, James L. Kennedy, Clement C. Zai, Arun K. Tiwari   +4 more
wiley   +1 more source

Noninvasive Prenatal Screening at Low Fetal Fraction: Comparing Whole-Genome Sequencing and Single-Nucleotide Polymorphism Methods [PDF]

, 2016
Carlo G. Artieri, Carrie Haverty, Eric A. Evans, Judith D. Goldberg, Imran S. Haque, Yuval Yaron, Dale Muzzey   +6 more
openalex   +1 more source

Pathway‐Informed Machine Learning Identifies Genetic Predictors of High‐Dose Methotrexate‐Induced Mucositis in Pediatric Acute Lymphoblastic Leukemia

Clinical Pharmacology &Therapeutics, EarlyView.
High‐dose methotrexate for pediatric cancer treatment is frequently associated with mucositis, which can lead to delayed or discontinued treatment and impact survival. While individual genetic variants have been implicated, the cumulative impact of genetic variation within relevant biological pathways remains unexplored.
Xiao Yu Cindy Zhang, Erika N. Scott, Hedy Maagdenberg, Alice Man, Kathy H. Li, S. Rod Rassekh, Bruce C. Carleton, Colin J. D. Ross, Wyeth W. Wasserman, Catrina M. Loucks   +9 more
wiley   +1 more source

The Genetic Structure and Diversity of Different Pigeon Breeds Based on a 5 K Single Nucleotide Polymorphism Chip. [PDF]

Animals (Basel)
Hou H, Li X, Wang X, Cai X, Tu Y, Lv W, Shen X, Yang C, Yao J.   +8 more
europepmc   +1 more source

Single nucleotide polymorphisms and penicillin non-susceptibility among invasive Streptococcus pneumoniae from Vietnam and India: Insights from a comparative genomics study

Avani Panickar, Anand Manoharan, Sudha Ramaiah   +2 more
openalex   +1 more source