Results 81 to 90 of about 4,995,337 (307)
Prediction of load transfer curves for single piles executed in granular soil profiles from field test measurements [PDF]
The load transfer methods are important tools for predicting the behavior of the load-displacement curve for piles. Several studies indicate that these curves in single piles can be well represented by hyperbolic functions. In this context, this research
Danton França da Silva +2 more
doaj +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Ground vibration measurements with special reference to pile driving [PDF]
There has been increased concern in recent years over the level and nature of the ground vibrations. The importance of such vibration has increased rapidly due to developments in construction in urban areas, where the effects of ground borne vibration on
Uromeihy, Ali, Uromeihy, A
core
Influences of compaction effect on bearing capacity of laterally loaded piles in sand
Displacement piles are widely adopted in practical engineering. Some of the piles are used to resist the horizontal cyclic loadings induced by wind or wave.
HU Kai 1, SU Dong 1,2, YU Zhong-liang 3, HUANG Jun-jie 1, PANG Xiao-chao 2, 4
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A literature review found no rigorous solution for the ultimate lateral pile-soil pressure ( ) in a soil characterised by a frictional failure criterion, and that the popular empirical methods to estimate give profiles with depth that differ ...
Pan, D.
core +1 more source
The muddy silty clay is rich in organic matter and widely distributed in Taihu soft soil foundation. It has a large water content and compressibility and is in a state of flow plasticity. All of these make it have bad engineering properties.
LI Hong-jiang 1,2, LIU Song-yu 1,2, TONG Li-yuan 1,2, HA Si 1,2, YANG Wan-yong 3
doaj +1 more source
Reduction of pile head displacement for restrained-head single pile
The effect of pile head fixity on the displacement of laterally loaded pile groups was investigated using analytical methods. The reduction of lateral displacement by a pile cap is generalized using a reduction factor, and the effect of soil and pile properties was investigated through a parametric study using the Davies and Budhu method.
Jinoh Won, Fred H. Kulhawy
openaire +1 more source

