Results 81 to 90 of about 4,995,337 (307)

Prediction of load transfer curves for single piles executed in granular soil profiles from field test measurements [PDF]

open access: yesREM: International Engineering Journal
The load transfer methods are important tools for predicting the behavior of the load-displacement curve for piles. Several studies indicate that these curves in single piles can be well represented by hyperbolic functions. In this context, this research
Danton França da Silva   +2 more
doaj   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Ground vibration measurements with special reference to pile driving [PDF]

open access: yes, 1990
There has been increased concern in recent years over the level and nature of the ground vibrations. The importance of such vibration has increased rapidly due to developments in construction in urban areas, where the effects of ground borne vibration on
Uromeihy, Ali, Uromeihy, A
core  

Influences of compaction effect on bearing capacity of laterally loaded piles in sand

open access: yesYantu gongcheng xuebao, 2019
Displacement piles are widely adopted in practical engineering. Some of the piles are used to resist the horizontal cyclic loadings induced by wind or wave.
HU Kai 1, SU Dong 1,2, YU Zhong-liang 3, HUANG Jun-jie 1, PANG Xiao-chao 2, 4
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Numerical modelling of rows of discrete piles used to stabilise landslides under long-term conditions in clays

open access: yes, 2013
A literature review found no rigorous solution for the ultimate lateral pile-soil pressure ( ) in a soil characterised by a frictional failure criterion, and that the popular empirical methods to estimate give profiles with depth that differ ...
Pan, D.
core   +1 more source

Case study and practical analysis of lateral bearing characteristics of a single pile in Taihu soft soils using CPTU data

open access: yesYantu gongcheng xuebao, 2018
The muddy silty clay is rich in organic matter and widely distributed in Taihu soft soil foundation. It has a large water content and compressibility and is in a state of flow plasticity. All of these make it have bad engineering properties.
LI Hong-jiang 1,2, LIU Song-yu 1,2, TONG Li-yuan 1,2, HA Si 1,2, YANG Wan-yong 3
doaj   +1 more source

Reduction of pile head displacement for restrained-head single pile

open access: yesKSCE Journal of Civil Engineering, 2009
The effect of pile head fixity on the displacement of laterally loaded pile groups was investigated using analytical methods. The reduction of lateral displacement by a pile cap is generalized using a reduction factor, and the effect of soil and pile properties was investigated through a parametric study using the Davies and Budhu method.
Jinoh Won, Fred H. Kulhawy
openaire   +1 more source

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