Results 51 to 60 of about 8,902,818 (343)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Merger of Rotation Restriction and Symmetrical Push‐Pull to Synthesize Single‐Benzene Yellow Fluorophors [PDF]

, 2023
Zimo Wang, Genki Horiguchi, Hidehiro Kamiya, Yohei Okada   +3 more
openalex   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Implementation of single-qubit gates with two rotations around axes in a plane

APL Quantum
Typical experimental implementations of single-qubit gates involve two or three fixed rotation axes and up to three rotation steps. In this work, we prove that if the rotation axes can be tuned arbitrarily in a fixed plane, then two rotation steps are ...
Yun-Pil Shim, Edward Takyi, Jianjia Fei, Sangchul Oh, Xuedong Hu, Mark Friesen   +5 more
doaj   +1 more source

Bidirectional optical rotation of cells

AIP Advances, 2017
Precise and controlled rotation manipulation of cells is extremely important in biological applications and biomedical studies. Particularly, bidirectional rotation manipulation of a single or multiple cells is a challenge for cell tomography and ...
Jiyi Wu, Weina Zhang, Juan Li
doaj   +1 more source

Single Channel Instrument for Simultaneous Rotation Speed and Vibration Measurement Based on Self-Mixing Speckle Interference [PDF]

, 2021
Xiulin Wang, Huiru Yang, Lu Hu, Zhen Li, Hanqiao Chen, Wencai Huang   +5 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Structures of the stator complex that drives rotation of the bacterial flagellum

bioRxiv, 2020
The bacterial flagellum is the prototypical protein nanomachine and comprises a rotating helical propeller attached to a membrane-embedded motor complex.
J. Deme, Steven Johnson, Owen N. Vickery, Amy Muellbauer, Holly Monkhouse, T. Griffiths, Rory Hennell James, B. Berks, J. Coulton, P. Stansfeld, S. Lea   +10 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Rotation Periods of Candidate Single Late-M Dwarfs in TESS

The Astronomical Journal
Recent studies suggest that the angular momentum evolution of late-M and brown dwarfs differs from the well-known spin-down evolution of hotter stars. Characterizing the distribution of rotation periods of these objects in the solar neighborhood can help
Samantha Lambier, Stanimir Metchev, Paulo Miles-Páez, Leslie Moranta, Dakota Wolfe, Joelene Hales, Jeffrey Martinovic   +6 more
doaj   +1 more source