Results 71 to 80 of about 1,532,926 (291)

Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids.

PLoS Biology, 2007
The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling of ...
Thorsten Hugel, Jens Michaelis, Craig L Hetherington, Paul J Jardine, Shelley Grimes, Jessica M Walter, Wayne Falk, Dwight L Anderson, Carlos Bustamante   +8 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Exploring the $P_{cyc}$ vs $P_{rot}$ relation with flux transport dynamo models of solar-like stars

, 2009
Aims: To understand stellar magnetism and to test the validity of the Babcock-Leighton flux transport mean field dynamo models with stellar activity observations Methods: 2-D mean field dynamo models at various rotation rates are computed with the STELEM
Brown, B. P., Brun, A. S., Jouve, L.
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Closed loop fiber optic rotation sensor [PDF]

, 1987
An improved optical gyroscope is provided, of the type that passes two light components in opposite directions through an optic fiber coil, and which adds a small variable frequency to one of the light components to cancel the phase shift due to rotation
Bartman, Randall K., Goss, Willis C., Nerheim, Noble M., Youmans, Bruce R.   +3 more
core   +1 more source

Atomic and photonic entanglement concentration via photonic Faraday rotation

, 2012
We propose two alternative entanglement concentration protocols (ECPs) using the Faraday rotation of photonic polarization. Through the single-photon input-output process in cavity QED, it is shown that the maximally entangled atomic (photonic) state can
Kuang, Le-Man, Liu, Xiao-Juan, Peng, Zhao-Hui, Xiao, Yong-Jun, Zou, Jian   +4 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Single versus dual-rate learning when exposed to Coriolis forces during reaching movements.

PLoS ONE, 2020
When we reach for an object during a passive whole body rotation, a tangential Coriolis force is generated on the arm. Yet, within a few trials, the brain adapts to this force so it does not disrupt the reach. Is this adaptation governed by a single-rate
Judith L Rudolph, Janny C Stapel, Luc P J Selen, W Pieter Medendorp   +3 more
doaj   +1 more source