Results 51 to 60 of about 1,532,926 (291)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Kepler Cluster Study: Stellar Rotation in NGC6811
, 2011 We present rotation periods for 71 single dwarf members of the open cluster NGC6811 determined using photometry from NASA's Kepler Mission. The results are the first from The Kepler Cluster Study which combine Kepler's photometry with ground-based ...
Barnes, Sydney A. +19 more
core +1 more source
New Rotation Sets in a Family of Torus Homeomorphisms [PDF]
, 2015 We construct a family $\{\Phi_t\}_{t\in[0,1]}$ of homeomorphisms of the two-torus isotopic to the identity, for which all of the rotation sets $\rho(\Phi_t)$ can be described explicitly.
Boyland, Philip +2 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Implementation of single-qubit gates with two rotations around axes in a plane
APL QuantumTypical experimental implementations of single-qubit gates involve two or three fixed rotation axes and up to three rotation steps. In this work, we prove that if the rotation axes can be tuned arbitrarily in a fixed plane, then two rotation steps are ...
Yun-Pil Shim +5 more
doaj +1 more source
Bidirectional optical rotation of cells
AIP Advances, 2017 Precise and controlled rotation manipulation of cells is extremely important in biological applications and biomedical studies. Particularly, bidirectional rotation manipulation of a single or multiple cells is a challenge for cell tomography and ...
Jiyi Wu, Weina Zhang, Juan Li
doaj +1 more source
Large anisotropy of spin-orbit interaction in a single InAs self-assembled quantum dot
, 2009 Anisotropy of spin-orbit interaction (SOI) is studied for a single uncapped InAs self-assembled quantum dot (SAQD) holding just a few electrons. The SOI energy is evaluated from anti-crossing or SOI induced hybridization between the ground and excited ...
Deacon, R. S. +6 more
core +1 more source
Utilising differences in rooting depth to design vegetable crop rotations with high nitrogen use efficiency (NUE) [PDF]
, 2002 A number of methods involving plant or soil analysis or modelling have been developed to optimise N fertilization of vegetable crops. The methods aim at improving the NUE of each single crop, but do not really consider the crop rotation as such.
Thorup-Kristensen, K
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Rotation Periods of Candidate Single Late-M Dwarfs in TESS
The Astronomical JournalRecent studies suggest that the angular momentum evolution of late-M and brown dwarfs differs from the well-known spin-down evolution of hotter stars. Characterizing the distribution of rotation periods of these objects in the solar neighborhood can help
Samantha Lambier +6 more
doaj +1 more source