Results 61 to 70 of about 1,532,926 (291)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Solution‐Processed Faraday Rotators Using Single Crystal Lead Halide Perovskites
Advanced Science, 2020 Lead halide perovskites (LHPs) have become a promising alternative for a wide range of optoelectronic devices, thanks to their solution‐processability and impressive optical and electrical properties. More recently, LHPs have been investigated in magneto‐
Randy P Sabatini +9 more
doaj +1 more source
Curvature Radiation in Rotating Pulsar Magnetosphere
, 2012 We consider the curvature emission properties from relativistic particles streaming along magnetic field lines and co-rotating with pulsar magnetosphere.
Backer +29 more
core +1 more source
Unitary equivalence between ordinary intelligent states and generalized intelligent states [PDF]
, 2007 Ordinary intelligent states (OIS) hold equality in the Heisenberg uncertainty relation involving two noncommuting observables {A, B}, whereas generalized intelligent states (GIS) do so in the more generalized uncertainty relation, the Schrodinger ...
E. Schrödinger +4 more
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Micromachines, 2018 Our group has reported that Melan-A cells and lymphocytes undergo self-rotation in a homogeneous AC electric field, and found that the rotation velocity of these cells is a key indicator to characterize their physical properties.
Yuliang Zhao +4 more
doaj +1 more source
Novel vortex structures in dipolar condensates
, 2005 We investigate the properties of single vortices and of vortex lattice in a rotating dipolar condensate. We show that vortices in this system possess many novel features induced by the long-range anisotropic dipolar interaction between particles.
H. Pu, L. M. Pismen, S. Yi
core +1 more source
Proof-of-principle demonstration of vertical gravity gradient measurement using a single proof mass double-loop atom interferometer [PDF]
, 2018 We demonstrate a proof-of-principle of direct Earth gravity gradient measurement with an atom interferometer-based gravity gradiomter using a single proof mass of cold 87 rubidium atoms.
Bidel, Yannick +5 more
core +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source