Results 51 to 60 of about 166,500 (329)

Analytical Expression for Low-dimensional Resonance Island in 4-dimensional Symplectic Map

, 2005
We study a 2- and a 4-dimensional nearly integrable symplectic maps using a singular perturbation method. Resonance island structures in the 2- and 4- dimensional maps are successfully obtained.
Goto, Shin-itiro
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transition of phase response properties and singularity in the circadian limit cycle of cultured cells. [PDF]

PLoS ONE, 2017
The circadian system has been regarded as a limit cycle oscillator constructed by the integrated interaction of clock genes and proteins. Here, we investigated a mammalian circadian oscillation geometrically before and after a perturbation.
Satoshi Koinuma, Hiroshi Kori, Isao T Tokuda, Kazuhiro Yagita, Yasufumi Shigeyoshi   +4 more
doaj   +1 more source

From exact-WKB towards singular quantum perturbation theory

, 2003
We use exact WKB analysis to derive some concrete formulae in singular quantum perturbation theory, for Schr\"odinger eigenvalue problems on the real line with polynomial potentials of the form $(q^M + g q^N)$, where $N>M>0$ even, and $g>0$.
Voros, André
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

On the Green function of linear evolution equations for a region with a boundary

, 2000
We derive a closed-form expression for the Green function of linear evolution equations with the Dirichlet boundary condition for an arbitrary region, based on the singular perturbation approach to boundary problems.Comment: 9 ...
Albeverio S, Berry M V, de Kronig L, Feynmann R, Fisher W, Gel'fand I M, George Krylov, Grosche C, Grosche C, Grosche C, Grosche C, Grosche C, Jakiw R, Kleinert H, Krylov G, Li Baowen, Marko Robnik, Morse P M, Prodan E, Watson G N   +19 more
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The failure of cosmological perturbation theory in the new ekpyrotic and cyclic ekpyrotic scenarios

, 2002
Cosmological perturbation theory fails in the new ekpyrotic and cyclic ekpyrotic scenarios, before the scale factor of the Universe reaches zero. As a result, a recently-proposed recipe for evolving the curvature perturbation through the bounce in these ...
Bardeen, Bardeen, Brandenberger, Brustein, Buonanno, David H. Lyth, Enqvist, Guth, Kallosh, Khoury, Khoury, Khoury, Kodama, Lidsey, Lyth, Lyth, Lyth, Lyth, Lyth, Lyth, Mukhanov, Olson, Sasaki, Steinhardt, Steinhardt, Veneziano   +25 more
core   +1 more source