Results 91 to 100 of about 299,137 (271)

Influence of cardiac tissue anisotropy on re-entrant activation in computational models of ventricular fibrillation

, 2009
The aim of this study was to establish the role played by anisotropic diffusion in (i) the number of filaments and epicardial phase singularities that sustain ventricular fibrillation in the heart, (ii) the lifetimes of filaments and phase singularities,
Clayton, R.H.
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Singularities of Type-Q ABS Equations

Symmetry, Integrability and Geometry: Methods and Applications, 2011
The type-Q equations lie on the top level of the hierarchy introduced by Adler, Bobenko and Suris (ABS) in their classification of discrete counterparts of KdV-type integrable partial differential equations.
James Atkinson
doaj   +1 more source

Deforming nonnormal isolated surface singularities and constructing 3-folds with $\mathbb{P}^1$ as exceptional set

, 2015
Normally one assumes isolated surface singularities to be normal. The purpose of this paper is to show that it can be useful to look at nonnormal singularities.
Stevens, Jan
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Three-Dimensional Scattering From Uniaxial Objects With a Smooth Boundary Using a Multiple Infinitesimal Dipole Method

IEEE Access, 2020
The formulations for three-dimensional (3D) scattering from uniaxial objects with a smooth boundary using a multiple infinitesimal dipole method (MIDM) are introduced.
Kai Wang, Jean-Jacques Laurin, Qingfeng Zhang, Qinyu Zhang, Ke Wu   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Singularities of multiplicative spherical Darboux image and multiplicative rectifying developable surface

Demonstratio Mathematica
In this study, singularity theory is used to explore the geometrical and topological properties of three types of curves and surfaces in multiplicative Euclidean space.
Li Jiaxin, Yao Xinyu, Ma Zikun, Liu Haiming   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

On Asymptotic Series for Generalized Airy, Circular, and Hyperbolic Functions

Mathematics
The paper concerns the solution of the ordinary differential equation y″±xmy=0, which may be designated the generalized Airy equation, since the original Airy equation corresponds to the particular case m=1 with the + sign.
Luiz M. B. C. Campos, Manuel J. S. Silva
doaj   +1 more source