Results 91 to 100 of about 295,670 (287)
, 1996 Contains fulltext : 257862.pdf (Publisher’s version ) (Open Access)
Jong, T. de, Steenbrink, J.H.M.
openaire +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Past singularities in phantom theories [PDF]
EAS Publications Series, 2008 4 pp. Uses eas.cls. Spanish Relativity Meeting ERE 2007: Relativistic Astrophysics and Cosmology. Eds: A. Oscoz, E. Mediavilla, M. Serra-Ricart. EAS Publications Series, Volume 30, EDP Sciences, Les Ulis, 131-136 (2008)
openaire +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Little string origin of surface defects
Journal of High Energy Physics, 2017 We derive a large class of codimension-two defects of 4d N = 4 $$ \mathcal{N}=4 $$ Super Yang-Mills (SYM) theory from the (2, 0) little string. The origin of the little string is type IIB theory compactified on an ADE singularity.
Nathan Haouzi, Christian Schmid
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Revisiting Schwarzschild black hole singularity through string theory
European Physical Journal C: Particles and FieldsIn this letter, we derive the singular condition for black holes and demonstrate the potential resolution of the Schwarzschild black hole singularity in general relativity using non-perturbative $$\alpha ^{\prime }$$ α ′ corrections of string theory ...
Houwen Wu, Zihan Yan, Shuxuan Ying
doaj +1 more source
International Journal of Advanced Robotic Systems, 2018 The traditional Denavit–Hatenberg method is a relatively mature method for modeling the kinematics of robots. However, it has an obvious drawback, in that the parameters of the Denavit–Hatenberg model are discontinuous, resulting in singularity when the ...
Rongbo Zhao +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source