Results 71 to 80 of about 295,670 (287)

Exact gravitational plane waves and two-dimensional gravity

Physics Letters B, 2018
We discuss dynamical aspects of gravitational plane waves in Einstein theory with massless scalar fields. The general analytic solution describes colliding gravitational waves with constant polarization, which interact with scalar waves and, for generic ...
Jorge G. Russo
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Five-dimensional SYM from undeformed ABJM

, 2011
We expand undeformed ABJM theory around the vacuum solution that was found in arxiv:0909.3101. This solution can be interpreted as a circle-bundle over a two-dimensional plane with a singularity at the origin.
A Gustavsson, A Gustavsson, Andreas Gustavsson, H Nastase, J Bagger, M Henningson, P Pasti, RP Andrews, S Terashima, S Terashima, T Banks, W Taylor, W Taylor   +12 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Positive solutions for singular $\phi-$Laplacian BVPs on the positive half-line

Electronic Journal of Qualitative Theory of Differential Equations, 2009
In this work, we are concerned with the existence of positive solutions for a $\phi$ Laplacian boundary value problem on the half-line. The results are proved using the fixed point index theory on cones of Banach spaces and the upper and lower solution ...
Smail Djebali, O. Saifi
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

T-duality across non-extremal horizons

Journal of High Energy Physics
When applying T-duality to a generic, non-extreme Killing horizon, T-duality is spacelike on one side and timelike on the other. We show, using simple examples from four-dimensional Einstein-Maxwell theory, that the image of the horizon is a singularity ...
M. Médevielle, T. Mohaupt
doaj   +1 more source

Schubert calculus and singularity theory

, 2011
Schubert calculus has been in the intersection of several fast developing areas of mathematics for a long time. Originally invented as the description of the cohomology of homogeneous spaces it has to be redesigned when applied to other generalized ...
Akyildiz, Arnold, Batyrev, Bertram, Boe, Borel, Borisov, Bourbaki, Bressler, Chair, Chaput, Chaput, Duan, Eguchi, Fendley, Freed, Gepner, Givental, Goresky, Gusein-Zade, Hertling, Hertling, Hori, Intriligator, Karasev, Knutson, Kostant, Lerche, Przyjalkowski, Saito, Siebert, Vafa, Vafa, Vassily Gorbounov, Victor Petrov, Witten   +35 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source