Results 51 to 60 of about 295,670 (287)
The Modelling and Control of a Singular Biological Economic System in a Polluted Environment
Discrete Dynamics in Nature and Society, 2016 A singular biological economic model with harvesting and stage structure is presented. The local stability of equilibriums of the system is investigated when the economic profit parameter is zero, and the conditions of the singularity induced bifurcation
Yi Zhang, Yueming Jie, Xinyou Meng
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Discrete gauging in six dimensions
Journal of High Energy Physics, 2018 When n M5 branes coincide on an A type singularity, ℂ2 /ℤ k , there is a multitude of tensionless strings which arise in the spectrum. The low energy theory when all M5 branes are separated at the singularity is given by a linear quiver with parameters n
Amihay Hanany, Gabi Zafrir
doaj +1 more source
Quantum dynamics corresponding to the chaotic BKL scenario
European Physical Journal C: Particles and Fields, 2023 We quantize the solution to the Belinski– Khalatnikov–Lifshitz (BKL) scenario using the integral quantization method. Quantization smears the gravitational singularity, preventing its localization in the configuration space.
Andrzej Góźdź +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Averaged energy conditions for vector fields
Physics Letters B, 2023 In this work we shall obtain sufficient conditions for the appearance of singularities in gravitational theories which propagate an extra vector degree of freedom, based on the known relaxations of the singularity theorems.
Francisco José Maldonado Torralba
doaj +1 more source
Strings vs Spins on the Null Orbifold
, 2014 We study the null orbifold singularity in 2+1 d flat space higher spin theory as well as string theory. Using the Chern-Simons formulation of 2+1 d Einstein gravity, we first observe that despite the singular nature of this geometry, the eigenvalues of ...
Kiran, K. Surya +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source