Results 51 to 60 of about 6,995,740 (255)
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara +7 more
wiley +1 more source
Singularity theory in classical cosmology [PDF]
This paper compares recent approaches appearing in the literature on the singularity problem for space-times with nonvanishing torsion.
openaire +3 more sources
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Spacelike singularities and string theory [PDF]
An interpretation of spacelike singularities in string theory uses target space duality to relate the collapsing Schwarzschild geometry near the singularity to an inflationary cosmology in dual variables. An appealing picture thus results whereby gravitational collapse seeds the formation of a new universe.
openaire +2 more sources
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
Black hole solutions in mimetic Born-Infeld gravity
The vacuum, static, and spherically symmetric solutions in the mimetic Born-Infeld gravity are studied. The mimetic Born-Infeld gravity is a reformulation of the Eddington-inspired-Born-Infeld (EiBI) model under the mimetic approach.
Che-Yu Chen +2 more
doaj +1 more source
Supersymmetric backgrounds in (1 + 1) dimensions and inhomogeneous field theory
We find a (1 + 1)-dimensional metric solution for a background hosting various supersymmetric field theories with a single non-chiral real supercharge. This supersymmetric background is globally hyperbolic even though it contains a naked null singularity.
Jeongwon Ho +3 more
doaj +1 more source
Deformation theory of sandwiched singularities
A sandwiched singularity is a normal surface singularity which admits a birational map to \(({\mathbb C},0)\). The paper under review is concerned with deformations of sandwiched singularities. Namely, deformations of sandwiched singularities are described via deformations of decorated curves.
Jong, T. de, Straten, D. van
openaire +4 more sources
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source

