Results 111 to 120 of about 68,175 (174)

Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

open access: yesStem Cells International, 2019
Background. Tbx18 is a vital transcription factor involved in embryonic sinoatrial node (SAN) formation process but is gradually vanished after birth.
Yannan Hu   +7 more
doaj   +1 more source

Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve [PDF]

open access: yesarXiv, 2019
Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart valves. This leads to risks of valve leaflet dysfunction, a life threatening event.
arxiv  

Dual network structure of the AV node [PDF]

open access: yesarXiv
Biological systems, particularly the brain, are frequently analyzed as networks, conveying mechanistic insights into their function and pathophysiology. This is the first study of a functional network of cardiac tissue. We use calcium imaging to obtain two functional networks in a subsidiary but essential pacemaker of the heart, the atrioventricular ...
arxiv  

Generation of an iPSC cell line (VANYHHi001-A) from a patient with cardiac arrythmias carrying CACNA1D, SCN5A, and DSP variants

open access: yesStem Cell Research
Progressive cardiac conduction defect often associated with variants in sodium voltage-gated channel SCN5A gene and variants in the L-type calcium voltage-gated channel CACNA1D gene are implicated in sinoatrial node dysfunction.
Yvonne Sleiman   +5 more
doaj  

Escitalopram-induced sinus bradycardia in coronary heart disease combined with depression: a case report and review of literature

open access: yesFrontiers in Cardiovascular Medicine
For patients with cardiovascular disease, using the antidepressant escitalopram may lead to unexpected adverse events. Here, a rare repeated sinus bradycardia event due to escitalopram is first reported.
Liu-Cheng Li   +7 more
doaj   +1 more source

Modeling familial sinus node dysfunction with a large intergenic deletion between PITX2 and ANK2 using iPS cell-derived sinoatrial nodal-like cardiomyocytes [PDF]

open access: bronze, 2023
Takanori Aizawa   +14 more
openalex   +1 more source

Sinoatrial Response to Premature Atrial Stimulation during Atrial Pacing in Aged Patients with and without Sinus Node Dysfunction

open access: bronze, 1978
Keiji Ueda   +7 more
openalex   +2 more sources

The effect of unhealthy lifestyle on the pathogenesis of sick sinus syndrome: A life-guiding review. [PDF]

open access: yesMedicine (Baltimore)
Chang X   +9 more
europepmc   +1 more source

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