Sinus Node Dysfunction, Atrial Arrhythmias, and the Sinus Node Microcirculation
A patient with sinus node dysfunction (SND) developed atrial arrhythmias that were abolished after avoidance of nonsteroidal anti-inflammatory medication and by the institution of a deliberate, modest increase in blood pressure, suggesting that there was
Susan K Fellner
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Ventricular pacing or dual-chamber pacing for sinus-node dysfunction [PDF]
BACKGROUND Dual-chamber (atrioventricular) and single-chamber (ventricular) pacing are alternative treatment approaches for sinus-node dysfunction that causes clinically significant bradycardia.
Ehlert, Frederick, , M.D. +18 more
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PITX2 dosage-dependent changes in pacemaker cell state underlie sinus node dysfunction and atrial arrhythmias [PDF]
Physiologically relevant increases in transcription factor dosage and their role in development and disease remain largely unexplored. Genomic deletions upstream of the Paired-like homeodomain transcription factor gene (PITX2), identified in patients ...
Lieve E. van der Maarel +16 more
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Oral theophylline corrects sinus node dysfunction in acute on chronic lithium toxicity: case report and systematic review of lithium-induced Sinus node dysfunction [PDF]
IntroductionLithium is a well-known agent to cause systemic toxicity with its narrow therapeutic window. Toxic cardiac effects are known but seldomly reported and can manifest as sinus node dysfunction (SND) ranging from delayed conduction to sinus ...
J. Curran Henson +4 more
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Use of machine learning and Poincaré density grid in the diagnosis of sinus node dysfunction caused by sinoatrial conduction block in dogs [PDF]
Background Sinus node dysfunction because of abnormal impulse generation or sinoatrial conduction block causes bradycardia that can be difficult to differentiate from high parasympathetic/low sympathetic modulation (HP/LSM).
Wyatt Hutson Flanders +2 more
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A case report of sinus node–sparing hybrid ablation for refractory sinus tachycardia following cardioneuroablation for sinus node dysfunction [PDF]
Background Cardioneuroablation (CNA) is increasingly used worldwide in the treatment of functional bradyarrhythmia mediated by excessive vagal tone. However, a potential early or long-term complication is the development of postprocedural inappropriate ...
Sebastian Stec +5 more
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Cardioneuroablation for the Treatment of Hypervagotonic Sinus Node Dysfunction [PDF]
Hypervagotonic sinus node dysfunction (SND) is a form of SND with sinus bradycardia caused by enhanced vagal tone. Indirect proof of hypervagotonia as the mechanism can be inferred from resolution of bradycardia following atropine infusion.
Arshneel Kochar, MD +6 more
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Sinus node dysfunction following bariatric surgery: A case report [PDF]
Sinus node dysfunction is often due to degeneration of the heart’s impulse-generating system. We report a case of a 40-year-old woman with a recent gastric sleeve surgery, who presented with symptomatic sinus bradycardia following significant post ...
Kristoffer Dahl, Knut Tore Lappegard
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Sinus node dysfunction (SND) refers to a wide range of abnormalities involving sinus node and atrial impulse generation and propagation. SND occurs at any age and is commonly encountered in clinical practice. Clinicians must be able to accurately diagnose this syndrome, which can present from asymptomatic bradycardia to atrial standstill.
Karla, Rusk, Kristine, Scordo
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Sinus node dysfunction is a multifaceted disorder with variable manifestations, the prevalence of which increases with age. In a specific group of patients, excessive vagal activity may be the sole cause for this condition.
Simin Cai, Lihui Zheng, Yan Yao
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