Results 51 to 60 of about 18,033 (268)

Brugada Syndrome: New Implications for Heterozygous Carriers of the Pathogenic SCN5A c.689T>C(p.Ile230Thr) Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in the SCN5A gene and its subunits have been identified in individuals with Brugada Syndrome. One such SCN5A variant, c.689T>C(p.Ile230Thr), was previously reported as disease‐causing only in homozygous individuals, with heterozygous carriers being unaffected.
Shayla Shojaat, Benjamin Hale, Taylor Warner   +2 more
wiley   +1 more source

SINUS NODE DYSFUNCTION IN CHILDREN [PDF]

Pediatric Research, 1977
Over a three year period, 30 pedlatric patients (pts) with electrocardiographic evidence of sinus node dysfunction (SND) were identified. Their ages ranged from 3 days to 21 years. Twenty-two pts had significant heart disease. In 13, the onset of SND followed corrective cardiac surgery, and of these, 8 were operations for atrial septal defect and ...
Steven M Yabek, Robert E Greenberg
openaire   +1 more source

Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide‐induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2

Animal Models and Experimental Medicine, EarlyView.
The interaction between mitofusin 2 (MFN2) and phosphofurin acidic cluster sorting protein 2 regulates the formation of mitochondria‐associated endoplasmic reticulum membranes (MAM). Overexpression of MFN2 can promote the formation of MAMs and inhibit inflammation and oxidative stress response in mammary epithelial cells.
Xiechen Zhou, Yufei Zhang, He Ma, Shoupeng Fu, Juxiong Liu, Wenjin Guo, Xiaofeng Tian, Bingxu Huang   +7 more
wiley   +1 more source

Sinus node dysfunction with interatrial conduction delay observed after left atrial myxoma resection through the superior septal approach

Journal of Arrhythmia, 2012
We report on a 64-year-old female patient who underwent cardiac surgery for left atrial myxoma, using the superior septal approach with large atrial septal wall resection and patch closure. The superior septal approach is reported to be a relatively safe
Susumu Miyazaki, Katsuhito Fujiu, Hiroaki Sugiyama, Takahide Murasawa, Jun Yokota, Keigo Iwazaki, Toshiya Kojima, Takeki Suzuki, Kazuo Asada, Hisayoshi Tamai, Yasushi Imai, Hiroshi Yamashita, Yasunobu Hirata, Ryozo Nagai   +13 more
doaj   +1 more source

Modeling familial sinus node dysfunction with a large intergenic deletion between PITX2 and ANK2 using iPS cell-derived sinoatrial nodal-like cardiomyocytes [PDF]

, 2023
Takanori Aizawa, Takeru Makiyama, Hiroshige Murata, Takashi Takaki, Manon Baudic, Jingshan Gao, Tomoko Imamura, Seiko Ohno, Yoshinori Yoshida, Wataru Shimizu, Naomasa Makita, Julien Barc, Jean‐Jacques Schott, Minoru Horie, Takeshi Kimura   +14 more
openalex   +1 more source

Commissural Misalignment Following Valve‐in‐Valve Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Data on commissural misalignment (CMA) during valve‐in‐valve transcatheter aortic valve implantation (ViV‐TAVI) for valve failure after surgical aortic valve replacement (SAVR) is scarce. Aims To study the impact of CMA on clinical and hemodynamic outcomes following ViV‐TAVI for failed SAVR.
Matthias Raschpichler, Johannes Rotta Detto Loria, Vivek Patel, Thilo Noack, Karoline Nüsser, Oliver Dumpies, Dhairya Patel, Takashi Nagasaka, Prateek Madaan, Aakriti Gupta, Holger Thiele, Michael A. Borger, Raj Makkar, Mohamed Abdel‐Wahab   +13 more
wiley   +1 more source

Transthyretin amyloid cardiomyopathy: Literature review and red‐flag symptom clusters for each cardiology specialty

ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.
Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya, Toru Kubo, Jin Endo, Seiji Takashio, Masatoshi Minamisawa, Jun Hamada, Tomonori Ishii, Hajime Abe, Hiroaki Konishi, Kenichi Tsujita   +9 more
wiley   +1 more source

Segmental Tracheal Resection for Thyroid Cancer: Perioperative Morbidity, Locoregional Control, and Survival

Head &Neck, EarlyView.
ABSTRACT Background Segmental tracheal resection is rarely needed for advanced thyroid cancer but is among the most complex, high‐risk thyroid surgeries. Methods Retrospective study of patients undergoing segmental tracheal resection for thyroid cancer at MD Anderson Cancer Center (2005–2024).
Anastasios Maniakas, David C. Wilde, Isabelle Fournier, Emily K. Hyde, Li Xu, Jennifer R. Wang, Neil D. Gross, Erich M. Sturgis, Victoria Banuchi, Naifa L. Busaidy, Maria E. Cabanillas, Priyanka Iyer, Ramona Dadu, Steven G. Waguespack, Mimi I. Hu, G. Brandon Gunn, Michael Kwon, Salmaan Ahmed, Michelle D. Williams, Mark E. Zafereo   +19 more
wiley   +1 more source

Familial sick sinus syndrome in two siblings

The Turkish Journal of Pediatrics, 1993
Two siblings with sinus node disease are presented. The patients were severely affected and required permanent pacing. A cardiac electrophysiologic study was conducted in Case 2, which revealed an atrioventricular conduction disturbance in ...
A Celiker, A Oto, S Ozme
doaj  

The Role of Electrophysiologic Study in Device Selection for Leadless Atrial Pacing [PDF]

Texas Heart Institute Journal
The AVEIR DR (Abbott Medical) was the first dual-chamber leadless pacing system approved by the US Food and Drug Administration. Many patients with sinus node dysfunction have physiologically normal atrioventricular conduction, so an atrial-only pacing ...
Joshua R. Hirsch, MD, Jordan M. Gales, MD, Irakli Giorgberidze, MD, Hamid Afshar, MD   +3 more
doaj   +1 more source