Results 181 to 190 of about 39,633 (292)

Pathological Ossification of Spinal Ligament‐Derived Fibroblasts in an Inflammatory Micro‐Environment via Activation of the ECM/ITGA5/FAK/AKT Pathway in Ankylosing Spondylitis

open access: yesCell Proliferation, EarlyView.
Schematic diagram illustrating the activation of the ECM/ITGA5/FAK/AKT axial signalling pathway in the osteogenic transdifferentiation of AS ligaments‐derived fibroblasts and the simulation of ectopic ossification via subcutaneous transplantation in vivo.
Mu Qiao   +7 more
wiley   +1 more source

Alterations of bone proteins in medication‐related osteonecrosis of the jaw

open access: yesEuropean Journal of Oral Sciences, Volume 133, Issue 2, April 2025.
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert   +6 more
wiley   +1 more source

Distinct collagen resolution dynamics in early versus advanced liver fibrosis: a quantitative SHG/TPEF study in mice. [PDF]

open access: yesInt J Clin Exp Pathol
Li H   +10 more
europepmc   +1 more source

Histological manifestations of vitamin A toxicity in the liver

open access: yesHistopathology, EarlyView.
Analysing clinicopathological data from 1960 to 2025, this study characterizes the spectrum of liver injury associated with chronic vitamin A toxicity. Hepatic stellate cell hypertrophy/hyperplasia and sinusoidal fibrosis emerge as the predominant features, providing a morphological basis for diagnosing vitamin A hepatotoxicity.
Giorgio Cazzaniga   +2 more
wiley   +1 more source

Biglycan Secreted by Tumor Stromal Cells Is a Predictive Marker for the Early Recurrence of Pancreatic Cancer. [PDF]

open access: yesPathol Int
Tanaka H   +11 more
europepmc   +1 more source

Lipidic obstruction of sinusoids (LOS): a potentially serious complication of steatotic liver disease

open access: yesHistopathology, EarlyView.
Lipidic obstruction of sinusoids is a particular histological pattern that can occur in fatty livers following liver damage and is characterized by extracellular fat deposition impairing sinusoidal blood flow. Introduction During routine examination of specimens from patients with steatotic liver disease (SLD), we repeatedly observed a peculiar ...
Katharina Endhardt   +6 more
wiley   +1 more source

Wiskott–Aldrich Syndrome Protein Is Required for Glucocorticoid‐Dependent Eosinopoiesis and Eosinophil‐Rich Inflammation in Murine Models

open access: yesImmunology, EarlyView.
WASP links GC‐dependent bone marrow eosinopoiesis to eosinophil‐rich allergic lung inflammation. GC‐responsive WASP+ stromal niche drives eosinopoiesis, generating eosinophilic lung inflammation and airway hyperresponsiveness. In WASP‐deficient allergic asthma, GC production and airway hyperresponsiveness are preserved, but GC‐driven bone marrow ...
Bruno Marques Vieira   +3 more
wiley   +1 more source

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