Results 11 to 20 of about 70,065 (194)

Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents. [PDF]

, 2007
BACKGROUND: The safety of drug-eluting stents has been called into question by recent reports of increased stent thrombosis, myocardial infarction, and death.
Kirtane, Ajay J, Schampaert, Erick, Dawkins, Keith D, Morice, Marie-Claude, Pocock, Stuart J, Fahy, Martin, Stone, Gregg W, Colombo, Antonio, Moses, Jeffrey W, Cutlip, Donald E, Ellis, Stephen G, Grube, Eberhard, Leon, Martin B, Mehran, Roxana, Schofer, Joachim   +14 more
core   +1 more source

Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction [PDF]

, 2002
Quantification of the new immunosuppressant sirolimus (syn. rapamycin; Rapamune((R))) in whole blood by chromatography is essential for its clinical use since no immunoassay is available although monitoring is mandatory.
Fleischer, Claudia, Groetzner, Jan, Spöhrer, Ute, Meiser, Bruno, Seidel, Dietrich, Vogeser, Michael   +5 more
core   +1 more source

Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]

, 2012
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P., Michael P. Ryan, O'Connell, Séin, Slattery, Craig, Tara McMorrow, Craig Slattery, Séin O'Connell, McMorrow, Tara   +7 more
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CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Continuous Subcutaneous Ketamine Infusion May Induce Tacrolimus and Sirolimus Clearance: A Case Report. [PDF]

Pharmacotherapy
ABSTRACT Background Drug interactions involving immunosuppressants can compromise transplant outcomes. Although repeated ketamine administration induces hepatic enzymes in experimental models, clinical reports of induced clearance of cytochrome P450 (CYP) substrates are lacking. Continuous subcutaneous ketamine infusions are increasingly used for acute
Stojanova J, Murnion B, Burrows F, Carlos L, Mizuno T, Nadai T, Irie K, Helsby N, Muthiah K, Day R.   +9 more
europepmc   +2 more sources

Systemic Treatment of Advanced Chordoma With Molecular Targeted Therapies: A Large Multicentre European Retrospective Case Series. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background This retrospective series reports outcomes and prognostic factors for advanced chordoma (AC) treatment with molecular targeted therapies (MTTs) in different treatment lines. Methods This is a retrospective series of 57 patients with AC treated between 2004 and 2023 at one of seven participating sarcoma centres.
Lipplaa A, Hindi N, Teterycz P, Young RJ, Boukonavis I, Cruz J, Martinez-Trufero J, Speetjens F, Peul W, van der Wal RJP, Gelderblom H.   +10 more
europepmc   +2 more sources

Additive value of transarterial embolization to systemic sirolimus treatment in kaposiform hemangioendothelioma. [PDF]

, 2020
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor in children, which can be accompanied by life-threatening thrombocytopenia, referred to as Kasabach-Merritt phenomenon (KMP).
Richard Brill, Huf, Veronika, Beate Häberle, Jacob Neumann, Moritz Wildgruber, Heid, Esther, Schinner, Regina, Sporns, Peter B., Wohlgemuth, Walter A., Lauten, Melchior, Wibke Uller, Till, Anne‐Marie, Regina Schinner, Brill, Richard, Häberle, Beate, Hüsemann, Dieter, Anne‐Marie Till, Schmidt, Vanessa F, Veronika Huf, Kapp, Friedrich G., Müller-Wille, René, René Müller‐Wille, Uller, Wibke, Dieter Hüsemann, Alexandra Pohl, Jens Ricke, Walter A. Wohlgemuth, Schmid, Axel, Jochen Rössler, Güttel, Christian, Peter B. Sporns, Friedrich G. Kapp, Schmidt, Vanessa F., Irene Schmid, Katrin Funke, Ricke, Jens, Ziermann, Franziska, Lutz Meyer, Meyer, Lutz, Schmid, Irene, Vanessa F. Schmidt, Esther Heid, Kapp, Friedrich G, Perkowski, Sybille, Till, Anne-Marie, Christian Güttel, Melchior Lauten, Sporns, Peter B, Sybille Perkowski, Rössler, Jochen, Wildgruber, Moritz, Pohl, Alexandra, Axel Schmid, Funke, Katrin, Neumann, Jacob, Franziska Ziermann, Müller‐Wille, René, Wohlgemuth, Walter A   +57 more
core   +1 more source

Sirolimus conversion regimen versus continued calcineurin inhibitors in liver allograft recipients: a randomized trial [PDF]

, 2012
A large prospective, open-label, randomized trial evaluated conversion from calcineurin inhibitor (CNI)- to sirolimus (SRL)-based immunosuppression for preservation of renal function in liver transplantation patients.
Barroso, E., Humar, A., Humar, A, Neff, G.W., Alberts, R G, Gane, E.J., Neff, GW, Toselli, L. T., Ranjan, D, Pascher, A., Pascher A, Neff GW, Scarola J, Barroso, E, Stickel, F., Andreone P, Abdelmalek, M.F., Sirolimus Liver Conversion Trial Study Group, Toselli LT, Ranjan, D., Neff, G W, Gane, E J, Barroso E, Toselli, LT, Lo, C.-M., Scarola, J., Lo, C-M, Pascher, A, Scarola, J, Maller, E. S., Abdelmalek MF, for the Sirolimus Liver Conversion Trial Study Group., Alberts RG, Gane, EJ, Andreone, P., ANDREONE, PIETRO, Abdelmalek, M. F., Toselli, L T, Ranjan D, Neff, G. W., Toselli, L.T., Alberts, R.G., Stickel F, Stickel, F, Maller, E S, Gane, E. J., , C.M. lo, Abdelmalek, MF, Maller, ES, Maller ES, Abdelmalek, M F, for the Sirolimus Liver Conversion Trial Study Group, Maller, E.S., Lo, CM, Alberts, R. G., Lo CM, Humar A, Sirolimus Liver Conversion Trial S, Gane EJ, Alberts, RG, Sirolimus Liver Conversion Trial Study Group,, Andreone, P   +61 more
core   +1 more source

A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

, 2010
Background: The potential anti-cancer effects of mammalian target of rapamycin (mTOR) inhibitors are being intensively studied. To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure ...
Pinna, Antonio D., HIDALGO E, Bechstein, Wolf Otto, M. Heise, Duvoux, Christophe, Heise, Michael, Lerut, Jan, Koert P de Jong, Valente Umberto, Heikki Mäkisalo, Rudolf Steininger, F. Fandrich, SCHMIDT J, Beckebaum, S., Troisi, Roberto I., V. Mazzaferro, Rene Adam, Burra P., Strasser Simone I, Becker, T., Lamby, P.E., Neuhaus Peter, A. Schnitzbauer, Rochon, Justine, Mirza Darius F, Faendrich, Fred, Geissler E. K. ., Fandrich, F., STEININGER R, HEISE M, P. E. Lamby, Rostaing L., Turrion Victor, Chazouilleres, O., VAN HOEK B, Soderdahl G., GRAEB C, Gerd Otto, Georges-Philippe Pageaux, Schlitt H. J., Neville Jamieson, Hans J Schlitt, BURRA P, MAZZAFERRO V, Jong, K.P. de, W. O. Bechstein, Makisalo, H., Rossi, Giorgio, KONIGSRAINER A, Rostaing, Lionel, Soderdahl Gunnar, Rizell, Magnus,, Turrion, V.S., Wolf, P., Strasser, S.I., Jauch, K.W., Philippe Wolf, Mazzaferro V., Wolters H., Pageaux, Georges-Philippe, ZUELKE C, Simone I Strasser, BECKER T, Kneteman N. M., Lerut, Jan P., Johann P Hauss, Duvoux Christophe, Wolters, Heiner, Jamieson N., Zuelke Carl, OTTO G, PINNA AD, Hauss J. P., I. Mutzbauer, Strasser, Simone I, Bilbao, I., Beckebaum Susanne, Schnitzbauer Andreas A, Mutzbauer I., Rizell M., Schmidt, Jan, Koenigsrainer, Alfred, Kneteman, Norman M., WOLTERS H, Lerut Jan P, G.E. Rossi, Gugenheim J., Tim Scholz, K. W. Jauch, N. Jamieson, Wolf O Bechstein, V. Sanchez Turrion, Rossi Giorgio, Andre Roy, van Hoek Bart, COLLEDAN M, Fändrich Fred, Olivier Chazouillères, Roy Andre, RIZELL M, Jan Schmidt, Gugenheim, J., Sanchez Turrion, Victor, K. P. De Jong, Neuhaus, P., R. Troisi, de Jong Koert P, R. Adam, Christophe Duvoux, L. Rostaing, Fandrich, Fred, Graeb, C., Lamby, Philipp E., Philipp E Lamby, Geissler Edward K, NEUHAUS P, A. D. Pinna, J. Pirenne, Pinna, A.D., Schnitzbauer, Andreas, VALENTE U, Pinna Antonio D, Adam Rene, U. Valente, STRASSER SI, Heiner Wolters, Margreiter Raimund, M. Colledan, BILBAO I, Geissler, Edward K., Lerut, Jan P, Chazouillères O., Troisi, Roberto, Heise M., Darius F Mirza, Wolters, H., Antonio D Pinna, M. Rizell, Fändrich F., HAUSS JP, MARGREITER R, O. Chazouilleres, DE JONG KP, Ingrid Mutzbauer, Karl-Walter Jauch, Schlitt, H.J., CHAZOUILLERES O, Victor Sanchez Turrion, Cillo U., Rochon J., Lamby, Philipp E, JAUCH KW, Andreas A Schnitzbauer, Burra, Patrizia, G. Soderdahl, LERUT JP, Mutzbauer, Ingrid, Graeb, Christian, Hauss Johann P, FANDRICH F, Scholz Tim, Strasser S. I., Pinna, Antonio D, BECKEBAUM S, Königsrainer A., Becker, Thomas, Rostaing Lionel, Gunnar Soderdahl, Colledan Michele, MAKISALO H, Roy, A., Makisalo, Heikki, I. Bilbao, U. Cillo, Turrion V. S., Justine Rochon, de Jong, Koert P, Umberto Cillo, Steininger, R., Hoek, Bart van, Gugenheim Jean, G. P. Pageaux, Mutzbauer, I., Geissler, E.K., Kneteman, Norman M, Margreiter, R., Fred Fändrich, Itxarone Bilbao, Edward K Geissler, Pirenne, J., Norman M Kneteman, Colledan M., Chazouilleres, Olivier, Gugenheim, Jean, Carl Zuelke, Magnus Rizell, N. M. Kneteman, Burra, P., Königsrainer Alfred, Bilbao, Itxarone, Otto G., Jacques Pirenne, P. Burra, Mazzaferro, Vincenzo, A. Konigsrainer, Schmidt Jan, E. Hidalgo, Mirza D. F., SODERDAHL G, Mazzaferro Vincenzo, Alfred Königsrainer, Heise, M., Otto Gerd, Margreiter R., Schlitt, Hans J., J. Rochon, Mäkisalo H., Cillo Umberto, Troisi Roberto I, Rossi G., T. Becker, Lamby Philipp E, Zuelke, Carl, ROY A, Scholz T., TURRION VS, Steininger R., Schlitt, Hans J, Schmidt, J., Lamby P. E., Graeb C., Bechstein W. O., Mirza, Darius F, Otto, G., Steininger, Rudolf, Raimund Margreiter, TROISI RI, Adam R., Pirenne, Jacques, Zuelke, C., Jauch K. W., Patrizia Burra, Scholz, Tim, Geissler, Edward K, Königsrainer, Alfred, J. Schimdt, Bechstein, W.O., Hidalgo, E., S. L. Strasser, PAGEAUX GP, Thomas Becker, Hidalgo E., A. Roy, Roy A., Pageaux, G.P., G. Otto, Schnitzbauer, A.A., Umberto Valente, MIRZA DF, Lerut J. P., Mirza, D.F., ADAM R, Colledan, Michele, Mäkisalo Heikki, Ernest Hidalgo, C. Zuelke, Pageaux Georges-Philippe, J. P. Hauss, J. Gugenheim, Roberto I Troisi, Bilbao I., Mazzaferro, V., Otto, Gerd, Cillo, Umberto, WOLF P, Rostaing, L., SCHLITT HJ, Neuhaus P., ROSSI G, Hauss, Johann P., Mutzbauer Ingrid, Vincenzo Mazzaferro, Jamieson, N., Jauch Karl-Walter, Chazouillères Olivier, Schnitzbauer A. A., Adam, R., Schmidt J., Strasser, Simone I., Bechstein Wolf O, Wolf Philippe, P. Neuhaus, C. Duvoux, Pirenne Jacques, Hauss, Johann P, Becker Thomas, D. F. Mirza, Bilbao Itxarone, Valente, U., P. Wolf, Bart van Hoek, Duvoux, C., T. Scholz, Jamieson, Neville, ROCHON J, Jan P Lerut, Pageaux G. P., Scholz, T., Lionel Rostaing, Schnitzbauer, Andreas A, MUTZBAUER I, Lerut, J.P., Rizell, Magnus, H. Wolters, Bechstein, Wolf O., Steininger Rudolf, BECHSTEIN WO, R. Steininger, B. Van Hoek, Konigsrainer, A., Becker T., Wolters Heiner, de Jong, Koert P., Roy, Andre, Kneteman Norman M, Bechstein, Wolf O, Troisi, Roberto I, Schnitzbauer, Andreas A., Schlitt Hans J, J. P. Lerut, PINNA, ANTONIO DANIELE, Burra Patrizia, SCHOLZ T, Wolf P., Christian Graeb, PIRENNE J, Beckebaum, Susanne, Rochon Justine, DUVOUX C, Adam, Rene, van Hoek B., Margreiter, Raimund, van Hoek, Bart, LAMBY PE, Jamieson Neville, S. Beckebaum, Pirenne J., Hidalgo Ernest, Soderdahl, Gunnar, GUGENHEIM J, Rochon, J., Jean Gugenheim, Giorgio Rossi, Hauss, J.P., Duvoux C., KNETEMAN NM, C. Graeb, Turrion, Victor Sanchez, Rizell, M., H. J. Schlitt, CILLO U, GEISSLER EK, SCHNITZBAUER AA, JAMIESON N, Jauch, Karl-Walter, H. Makisalo, Beckebaum S., Peter Neuhaus, R. Margreiter, Rizell Magnus, Kneteman, N.M., Mirza, Darius F., E. K. Geissler, Rossi, G., Heise Michael, Michael Heise, Hoek, B. van, Hidalgo, Ernest, Michele Colledan, Wolf, Philippe, Troisi R. I., Zuelke C., Valente, Umberto, Neuhaus, Peter, Valente U., Soderdahl, G., ROSTAING L, de Jong K. P., Cillo, U., Graeb Christian, Susanne Beckebaum, Troisi, R.I., Colledan, M.   +392 more
core   +1 more source