Results 31 to 40 of about 66,662 (177)
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background In the REFORM trial, treatment of coronary in‐stent restenosis with a Biolimus A9™ drug‐coated balloon (BCB) was found to be inferior with respect to in‐segment percentage stenosis at 6‐months in comparison to treatment with a standard paclitaxel coated paclitaxel‐coated balloon (PCB). Aims In this manuscript, the final prespecified
Daniel O'Callaghan +18 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2018 Background Sirolimus has been shown to be effective in patients with lymphangioleiomyomatosis (LAM). We wish to summarize our experience using sirolimus and its effectiveness in LAM patients.
Yongzhong Zhan +9 more
doaj +1 more source
Acute sirolimus overdose: a multicenter case series. [PDF]
PLoS ONE, 2015 There are few data relating to sirolimus overdose in the medical literature. Our objectives were to describe all cases of overdose with sirolimus reported to Swiss, German and Austrian Poisons Centres between 2002-2013.An observational case-series ...
Alessandro Ceschi +7 more
doaj +1 more source
Sirolimus-Induced Rash in a Kidney Transplant Patient
European Journal of Case Reports in Internal Medicine, 2022 Sirolimus is an inhibitor of the mammalian target of rapamycin, which is used in kidney transplant immunosuppression. The clinical spectrum of cutaneous adverse events associated with sirolimus use varies, with maculopapular rash being an uncommon side ...
Zachary Bruss +3 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Optimal stent expansion is a key determinant of long‐term outcomes after PCI. Intravascular imaging provides the most accurate assessment of stent deployment but remains underused, especially in older patients with MI and multivessel disease.
Marta Cocco +12 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Limited data are available on the use of intravascular ultrasound (IVUS) in patients presenting with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess the impact of IVUS‐guided primary percutaneous coronary intervention (PCI).
Frederik T. W. Groenland +13 more
wiley +1 more source
Drug Interaction between Sirolimus and Ranolazine in a Kidney Transplant Patient
Case Reports in Transplantation, 2014 Purpose. The case of a kidney transplant recipient who experienced a probable drug interaction between sirolimus and ranolazine is reported. Summary.
Joanna C. Masters +2 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background Biodegradable‐polymer (BP) drug‐eluting stents (DES) were developed to mitigate potential late adverse events related to persistent durable polymers in durable‐polymer (DP) DES; however, contemporary long‐term real‐world comparative data remain limited. Aims We aimed to compare the 5‐year clinical outcomes of contemporary BP‐DES and
Yangyoun Lee +6 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
Clinical and Translational ScienceDose optimization of sirolimus may further improve outcomes in allogeneic hematopoietic cell transplant (HCT) patients receiving post‐transplantation cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD).
Ezhilpavai Mohanan +11 more
doaj +1 more source