Results 51 to 60 of about 70,065 (194)
ABSTRACT Background/Objectives Pediatric patients with epidermolysis bullosa (EB) experience lifelong complications, and wound healing is an important treatment goal. In the phase III EASE study (NCT03068780), Oleogel‐S10 accelerated wound healing in EB.
Eli Sprecher +16 more
wiley +1 more source
Sirolimus (SRL) is a potent immunosuppressant with a long elimination half-life. Steady-state trough concentration (C0 or C24) is a reliable index of its exposure. This study was designed to understand the influence of sampling time on SRL C24.
LIN, FE-LIN;TSAI, MENG-KUNG;SUN, SHAO-WEN;YU, WEN-YING;LEE, PO-HUANG +1 more
core
The Top Five Advances in Solid Organ Transplantation in the Past Fifty Years
World Journal of Surgery, EarlyView.
Stephen J. Wigmore, Diana A. Wu
wiley +1 more source
The role of acquired host immunity in periodontal diseases
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
Ha Na Woo1*, Hye Kyung Chung2*, Eun Jin Ju1, Joohee Jung1,3, Hye-Won Kang4, Sa-Won Lee4, Min-Hyo Seo4, Jin Seong Lee5, Jung Shin Lee1,6, Heon Joo Park7, Si Yeol Song1,8, Seong-Yun Jeong1, Eun Kyung Choi1,2,81Institute for Innovative Cancer Research ...
Lee JS +11 more
core
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Optimized formulation of solid self-microemulsifying sirolimus delivery systems
Wonkyung Cho,1,2 Min-Soo Kim,3 Jeong-Soo Kim,2 Junsung Park,1,2 Hee Jun Park,1,2 Kwang-Ho Cha,1,2 Jeong-Sook Park,2 Sung-Joo Hwang1,4 1Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea; 2College of Pharmacy ...
Cho W +7 more
core
Sirolimus and secondary skin-cancer prevention in kidney transplantation [PDF]
BACKGROUND: Transplant recipients in whom cutaneous squamous-cell carcinomas develop are at high risk for multiple subsequent skin cancers. Whether sirolimus is useful in the prevention of secondary skin cancer has not been assessed.
Broeders, Emine Nilufer +30 more
core +1 more source
An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley +1 more source
Sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. Sirolimus must be used within a narrow therapeutic window.
Mohammad Javad Khoshnoud +3 more
core +1 more source

