Results 41 to 50 of about 70,065 (194)

Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali   +5 more
wiley   +1 more source

器官移植病人calcineurin抑制劑及 Sirolimus之療劑監測

open access: yes, 2009
由於Calcineurin inhibitors(CNIs,包括cyclosporine與tacrolimus)與 sirolimus(SRL)在長期預防排斥用藥中,屬於效價最強的免疫抑制劑,須仰賴血中 濃度、副作用與排斥反應等因素來決定個別病人的最低有效劑量,醫療人員因此需對 其療劑監測(therapeutic drug monitoring;TDM)與臨床藥品動態學(簡稱臨床藥 動學)有相當的了解。本文整理許多表格比較CNIs與sirolimus製劑、劑量、藥動學 性質、檢測方法(包括谷濃度 ...
LIN, FE-LIN;TSAI, MENG-KUNG;LEE, PO-HUANG;SUN, SHAO-WEN;CHUEH, SHIH-CHIEH;CHEN, RUSSEL RHEI-LONG   +1 more
core  

Sirolimus induced granulomatous interstitial pneumonitis

open access: yes, 2012
ObjectivesReport a case of sirolimus induced granulomatous pneumonitis.BackgroundSirolimus is used in clinical transplantation as an immunosuppressive agent.
Elsanjak, Abdelaziz   +4 more
core   +1 more source

Immune checkpoint inhibitor‐induced eosinophilic fasciitis: A pharmacovigilance and EADV Task force study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
A comprehensive retrospective analysis of 121 immune checkpoint inhibitor‐induced eosinophilic fasciitis cases, including clinical presentation, diagnostic features and treatment outcomes using data from the EADV Task Force ‘Dermatology for Cancer Patients’, two international pharmacovigilance databases and the current literature.
Tristan V. M. Bruijn   +17 more
wiley   +1 more source

Sirolimus-eluting coronary stents: a review

open access: yes, 2007
Alexandre AbizaidInstitute Dante Pazzanese of Cardiology, Sao Paulo, BrazilAbstract: The sirolimus-eluting coronary stent received CE Mark approval in Europe in April 2002. In the US, FDA approval followed in April 2003.
Alexandre Abizaid
core  

Pneumopathie médicamenteuse sous sirolimus : interaction avec l’atorvastatine ?

open access: yes, 2012
Introduction Sirolimus is an immunosupressant used in renal transplantation because of its lack of nephrotoxicity. We report four cases of pneumonitis due to sirolimus, possibly revealing an interaction with atorvastatin.
O. Molinier   +14 more
core   +1 more source

Management of Kaposiform Haemangioendothelioma—A Retrospective Case Series Examining the Use and Effectiveness of Vincristine

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Kaposiform haemangioendothelioma is a rare vascular tumour. Management has evolved over the last two decades, with most cases receiving vincristine or sirolimus. We aim to describe our experience with managing this tumour, with a focus on the safety and efficacy of vincristine.
Bronwen Kirk   +4 more
wiley   +1 more source

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process

open access: yes, 2011
Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei ...
Hwang SJ   +5 more
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Therapy With Doxycycline and Hydroxychloroquine Enables Surgical Excision of Ulcerated Cutaneous Granulomas in a Patient With Ataxia Telangiectasia

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT The rubella virus vaccine strain can cause granulomas in patients with inborn errors of immunity that may evolve into chronic, recalcitrant ulcers. This report details treatment of ulcerated rubella granulomas in a patient with ataxia telangiectasia with doxycycline and hydroxychloroquine resulting in partial ulcer healing within 4 weeks ...
Luis Murguía‐Favela   +6 more
wiley   +1 more source

台灣穩定腎移植病人由sirolimus口服 液轉換成錠劑的影響

open access: yes, 2009
Background and purpose: Sirolimus (SRL) has a considerable inter and intra- individual variability in clearance. Steady -state trough concentration (C0) is a reliable index of SRL exposure.
林慧玲;蔡孟昆;孫紹文;陳瑞龍;黃金鼎;李伯皇   +1 more
core  

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