Results 91 to 100 of about 35,822 (223)

Sequential 90Y Selective Internal Radiation Therapy (SIRT) and Stereotactic Body Radiation Therapy (SBRT) using 90Y PET-based Absorbed Dose Maps: Interim Analysis of a Phase 1 Study

Advances in Radiation Oncology
Purpose: Selective internal radiation therapy (SIRT) can result in heterogeneous absorbed dose coverage. To address potential underdosing of lesions with SIRT, we designed a phase 1 clinical trial (NCT04518748) to add stereotactic body radiation therapy (
Daniel F. Polan, PhD, Justin K. Mikell, PhD, Kellen Fitzpatrick, MS, Joseph J. Gemmete, MD, Jared A. Christensen, MD, Hassan Anbari, MD, Molly Roseland, MD, Joseph R. Evans, MD, PhD, Daniel T. Chang, MD, Mamadou Sanogo, MD, Baljendra S. Kapoor, MD, Matthew J. Schipper, PhD, Yue Cao, PhD, Madhava P. Aryal, Theodore S. Lawrence, MD, PhD, Kyle C. Cuneo, MD, Yuni K. Dewaraja, PhD   +16 more
doaj   +1 more source

National survey of real‐world treatment patterns for early‐ and intermediate‐stage hepatocellular carcinoma reveals wide variation across Australian states

Internal Medicine Journal, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a heterogeneous and multi‐disease state that is complex to manage and requires a multidisciplinary approach to optimise patient care. Best practice recommendations were proposed in the Australian HCC consensus statement published in 2020.
Stuart K. Roberts, Ammar Majeed, Kiran Rasaratnam, John K. Olynyk, Nicholas Shackel, Marnie Wood, Alan Wigg, Simone I. Strasser   +7 more
wiley   +1 more source

Analysis of the SIRT Gene Family of Danio rerio and Its Expression at Different Developmental Stages of Follicles

Progress in Fishery Sciences
SIRT family is a NAD+ dependent class Ⅲ deacetylase family, which is involved in the modification of histone or non-histone proteins. In addition to having deacetylase, some members of the SIRT family also have ADP-ribosylase and other activities, which ...
Jiabao PENG, Ziyan WANG, Zhigang YANG, Aqin CHEN   +3 more
doaj   +1 more source

Application of Noise2Inverse and adaptation (Noise2Phase) to single‐mask x‐ray phase contrast micro‐computed tomography

Journal of Microscopy, EarlyView.
Abstract X‐ray phase contrast imaging (XPCI), when implemented in micro‐computed tomography (micro‐CT) mode, offers high‐contrast 3D imaging of weakly‐attenuating material samples. In the so‐called single‐mask edge illumination approach, a mask with periodically spaced transmitting apertures is used to split the x‐ray beam into narrow beamlets; when ...
Khushal Shah, Grammatiki Lioliou, Dai Chen, Alexander Denker, Peter Munro, Marco Endrizzi, Alberto Astolfo, Alessandro Olivo, Charlotte K. Hagen   +8 more
wiley   +1 more source

Patterns of information security postures for socio-technical systems and systems-of-systems [PDF]

, 2012
This paper describes a proposal to develop patterns of security postures for computer based socio-technical systems and systems-of-systems.
Glisson, W., Renaud, K., Storer, T.
core  

An open label investigation of the feasibility and effectiveness of Memory Boost: A novel brief group cognitive remediation intervention for adults with mixed mood and anxiety disorders

Journal of Neuropsychology, EarlyView.
Abstract To evaluate the feasibility and effectiveness of a novel group cognitive remediation (Memory Boost) designed to improve memory in an adult mixed mood and anxiety disorder population. A secondary aim was to explore the relationship between mood symptoms and performance on subjective and objective memory measures.
Catherine Bosyj, Jelena P. King, Christina Gojmerac, Bruno Losier, Heather E. McNeely   +4 more
wiley   +1 more source

E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Mediators of Inflammation, 2013
Background. Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. These SIRT actions involve the nuclear factor κB and its inhibitor IκB pathway.
Angela Storka, Gerhard Führlinger, Martin Seper, Lisa Wang, Michael Jew, Asha Leisser, Michael Wolzt   +6 more
doaj   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

Geochemical Evaluation of Campanian Sirte Shale Source Rock, Arshad Area, Sirt Basin, Libya

IOSR Journal of Applied Geology and Geophysics, 2014
The present geochemical study deals with evaluation of Sirte Shale (Campanian) source rock in Arshad area which is located in the central Sirt Basin in north central Libya. Sirte Formation is composed mainly of shale, sandy shale, being partially sandy and calcareous facies indicating presence of possible source rocks.
KhaledK KhaledK, Darwish M, Abu Khadra A, Burki M   +3 more
openaire   +1 more source

Consumption of a High-Fat Meal Alters Post-Prandial SIRT mRNA Expression in Blood Leukocytes [PDF]

, 2015
Introduction. Sirtuins (SIRT) are protein deacetylases, hypothesized to regulate the transcription of various genes involved in the prevention of atherogenesis and diet induced obesity.
Henning, Andrea L, McFarlin, Brian K, Padilla, Pamela, Prado, Eric A, Sampson, Jill N, Venable, Adam   +5 more
core   +1 more source