Results 101 to 110 of about 22,785 (248)

Tectonics and subsidence evolution of the Sirt Basin, Libya

AAPG Bulletin, 2005
Abstract A backstripping analysis of 225 wells located within the Sirt Basin, Libya, provides new constraints on the development of the Sirt Basin. Four tectonic phases are identified from Late Jurassic to present. The presentation of contour maps of subsidence and crustal stretching allows spatial and temporal variations in ...
Abadi, A.M., Wees, J.D. van, Dijk, P.M. van, Cloetingh, S.A.P.L.   +3 more
openaire   +4 more sources

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Mediators of Inflammation, 2013
Background. Sirtuin (SIRT) proteins are class I histone deacetylases displaying gene regulatory functions in inflammatory, cancer, and metabolic diseases. These SIRT actions involve the nuclear factor κB and its inhibitor IκB pathway.
Angela Storka, Gerhard Führlinger, Martin Seper, Lisa Wang, Michael Jew, Asha Leisser, Michael Wolzt   +6 more
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Application of Noise2Inverse and adaptation (Noise2Phase) to single‐mask x‐ray phase contrast micro‐computed tomography

Journal of Microscopy, EarlyView.
Abstract X‐ray phase contrast imaging (XPCI), when implemented in micro‐computed tomography (micro‐CT) mode, offers high‐contrast 3D imaging of weakly‐attenuating material samples. In the so‐called single‐mask edge illumination approach, a mask with periodically spaced transmitting apertures is used to split the x‐ray beam into narrow beamlets; when ...
Khushal Shah, Grammatiki Lioliou, Dai Chen, Alexander Denker, Peter Munro, Marco Endrizzi, Alberto Astolfo, Alessandro Olivo, Charlotte K. Hagen   +8 more
wiley   +1 more source

SIRT and alternative palliative treatment methods for liver carcinomas

, 2018
Die vorgelegte Bachelorarbeit befasst sich mit einem empirischen Studienvergleich mit anschließender tabellarischer Gegenüberstellung der Ergebnisse. Es wurden palliative Behandlungsmethoden des HCCs, die SIRT, TACE, HIFU, RFA und PEI vergleichen.
Nikolic, Filip
core   +2 more sources

Role of sirtuins in epigenetic regulation and aging control

Вавиловский журнал генетики и селекции
Advances in modern healthcare in developed countries make it possible to extend the human lifespan, which is why maintaining active longevity is becoming increasingly important.
E. M. Samoilova, S. E. Romanov, D.  A. Chudakova, P. P. Laktionov   +3 more
doaj   +1 more source

The role and therapeutic potential of SIRTs in sepsis

Frontiers in Immunology
Sepsis is a life-threatening organ dysfunction caused by the host’s dysfunctional response to infection. Abnormal activation of the immune system and disturbance of energy metabolism play a key role in the development of sepsis. In recent years, the Sirtuins (SIRTs) family has been found to play an important role in the pathogenesis of sepsis.
Jiaqi You, Yilin Li, Wei Chong
openaire   +3 more sources

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-associated steatotic liver disease

BMC Gastroenterology
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease and can affect individuals without producing any symptoms.
Farshad Amirkhizi, Mahdiyeh Taghizadeh, Banafshe Khalese-Ranjbar, Soudabeh Hamedi-Shahraki, Somayyeh Asghari   +4 more
doaj   +1 more source