Securidaca inappendiculata Extract Mitigates Joint Damage in Collagen-Induced Arthritis Rats Through Modulation of the SIRT1/HIF-1α/Glycolysis Pathway. [PDF]
Zhou Y +6 more
europepmc +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Anthocyanin-Rich <i>Morus alba</i> L. Fruit Extract Phytosome Protects Neuronal Cells Against Oxidative Stress-Induced Cytotoxicity. [PDF]
Khongrum J, Palachai N.
europepmc +1 more source
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves +3 more
wiley +1 more source
Protective effect of <i>Panax ginseng</i> on AlCl₃-induced liver, kidney, and testis toxicity in male albino rats: biochemical, histopathological, and molecular study. [PDF]
Al-Saeed FA, Ghfar SSA, Ali ME.
europepmc +1 more source
Abstract We compared the acute and chronic effects of postexercise cold water immersion (CWI) and active recovery (ACT) on oxidative stress, redox‐related gene expression, mitochondrial adaptations and muscle oxidative capacity. In a crossover study, nine males completed strength sessions, followed by either 10 min CWI or ACT.
Llion A. Roberts +10 more
wiley +1 more source
A candidate PPARγ to GPX4 axis in ferroptosis suppression and platinum resistance in bladder cancer: evidence appraisal and a testable research agenda. [PDF]
Li S +11 more
europepmc +1 more source
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley +1 more source
ERα/SIRT1 signaling mediates the metabolic regulatory benefits of pterostilbene. [PDF]
Huang T +7 more
europepmc +1 more source
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera +8 more
wiley +1 more source

