Results 201 to 210 of about 65,348 (268)

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler   +2 more
wiley   +1 more source

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

open access: yesExperimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves   +3 more
wiley   +1 more source

Effects of cold water immersion versus active recovery on oxidative stress, redox gene expression and mitochondrial adaptations after strength training

open access: yesExperimental Physiology, EarlyView.
Abstract We compared the acute and chronic effects of postexercise cold water immersion (CWI) and active recovery (ACT) on oxidative stress, redox‐related gene expression, mitochondrial adaptations and muscle oxidative capacity. In a crossover study, nine males completed strength sessions, followed by either 10 min CWI or ACT.
Llion A. Roberts   +10 more
wiley   +1 more source

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

open access: yesExperimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

ERα/SIRT1 signaling mediates the metabolic regulatory benefits of pterostilbene. [PDF]

open access: yesJ Biol Chem
Huang T   +7 more
europepmc   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

open access: yesExperimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera   +8 more
wiley   +1 more source

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