Results 321 to 330 of about 84,834 (402)

Multi‐Target Modulation of Polyphenols in Diabetic Kidney Disease Therapeutics: A Comprehensive Review

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
This review shows evidence from preclinical and clinical studies, supporting the therapeutic potential of polyphenols for diabetic kidney disease (DKD). This is due to their diverse bioactive properties and ability to intervene in intricate mechanisms of the disease.
Esienanwan E. Efiong, Emmanuel Effa, Esther Peters, Ochuko L. Erukainure, Peter U. Amadi, Joshua Onyeka Ikebuiro, Sapna Sharma, Christoph Schmaderer, Kathrin Maedler, Emmy Tuenter, Harald Grallert   +10 more
wiley   +1 more source

SIRT5 is associated with asthenozoospermia and regulates GC‑2 spd cell proliferation and apoptosis. [PDF]

Mol Med Rep
Xing H, Chen S, Wang M, Zheng T, Yang B.
europepmc   +1 more source

RETRACTED: Sirtuin-4 modulates sensitivity to induction of the mitochondrial permeability transition pore

, 2012
Manish Verma, Nataly Shulga, John G. Pastorino   +2 more
openalex   +1 more source

Antioxidant Properties of Whey Protein‐Derived Peptides: Radical Scavenging and Cytoprotective Effects

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
In this study, whey protein hydrolysate was fractionated and several antioxidant peptides were identified from the fraction with high H‐ORAC activity. These peptides exhibited H‐ORAC, DPPH, and ABTS radical scavenging activity and cytoprotective effects in C2C12 cells.
Ryota Suzuki, Sayuri Arai, Masaki Kurimoto, Naoki Yuda, Miyuki Tanaka   +4 more
wiley   +1 more source

Celastrol modulates IRS1 expression to alleviate ovarian aging and to enhance follicular development. [PDF]

Cell Biol Toxicol
Jiang Y, Shi Y, Lv M, Wang T, Wang P, Yuan X, Gao F, Ma B.   +7 more
europepmc   +1 more source

The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1

, 2012
Gabriel Frampton, Yoshiyuki Ueno, Matthew Quinn, Matthew McMillin, Hae Yong Pae, Cheryl Galindo, Dinorah Leyva‐Illades, Sharon DeMorrow   +7 more
openalex   +2 more sources

Nicotinamide phosphoribosyltransferase (Nampt) in Lateral Hypothalamus Maintains Skeletal Muscle Functions Through Lactate‐Mediated Calcium Signalling in Male Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Sarcopenia has become an urgent socioeconomic problem in rapidly aging societies. The pathogenesis of age‐associated sarcopenia is not fully understood and no effective therapeutic strategies have been developed to date. Recent studies have suggested the importance of the functional linkage between the brain and skeletal muscles in ...
Takahiro Eguchi, Keiko Kabetani, Naoki Ito   +2 more
wiley   +1 more source

gdSir2.1 and gdSir2.3 are involved in albendazole resistance in Giardia duodenalis via regulation of the oxidative stress response. [PDF]

Int J Parasitol Drugs Drug Resist
Chávez-Cano A, Dawson SC, Guadalupe Ortega-Pierres M.   +2 more
europepmc   +1 more source

Sirtuin-1 mediates the obesity induced risk of common degenerative diseases: Alzheimer’s disease, coronary artery disease and type 2 diabetes

, 2012
Ian Martins, Andrea C. Wilson, Wei Ling Florence Lim, Simon M. Laws, Stephanie Fuller, Ralph N. Martins   +5 more
openalex   +2 more sources

Enhancing Muscle Quality: Exploring Leucine and Whey Protein in Sarcopenic Individuals

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Sarcopenia is characterised by a decline in the skeletal muscle mass with increasing age. This poses many challenges to the health and independence of older individuals. New and emerging studies have focused on supplementing leucine‐enriched whey protein and resistance training in older adults to mitigate the effects of sarcopenia ...
Aiman Ijaz, Huma Bader Ul Ain, Tabussam Tufail, Raima Mariam, Sana Noreen, Aniqa Amjad, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +8 more
wiley   +1 more source