Results 331 to 340 of about 84,834 (402)

Epigallocatechin-3-Gallate from Green Tea Reduces Vascular Aging and Endothelial Cell Senescence by Modifying Autophagy and Ferroptosis through the Sirtuin 1 Signaling Pathway. [PDF]

ACS Omega
Zhang Y, Wang T, Wang L, Fang Z, Lu T, Chen S, Yan J, Qin C, Shen X, Kang N, Tian L, Cao F.   +11 more
europepmc   +1 more source

A Big Step for SIRT7, One Giant Leap for Sirtuins… in Cancer

, 2012
Paloma Martínez‐Redondo, Irene Santos‐Barriopedro, Alejandro Vaquero   +2 more
openalex   +1 more source

Engineering Efferocytosis for Bone Regeneration

Macromolecular Bioscience, Volume 25, Issue 10, October 2025.
The repair of bone tissue in acute and chronic injuries is a significant long‐standing clinical challenge. Biomaterials‐based interventions are well‐positioned to interrogate mechanisms of efferocytosis due to their ability to provide support and guide cellular activity.
Jacob Miszuk, Linna Zhong, Hongli Sun
wiley   +1 more source

The crosstalk between MicroRNAs and sirtuins: a bit unexpected therapeutic target for cardiovascular diseases. [PDF]

Eur J Med Res
Kamvar R, Barjasteh AH, Omouri-Kharashtomi M, Roumiani PH, Beheshtirooy A, Adib-Hajbagheri P, Rezaei P, Shokraei R, Pourhanifeh MH.   +8 more
europepmc   +1 more source

Free Radicals in Health and Disease

MedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source

The mechanism and therapeutic potential of SIRT3 in central nervous system diseases: a review. [PDF]

Front Pharmacol
Hong C, Wei Y, Wang Y, Lv G, Dong X, Huang X.   +5 more
europepmc   +1 more source

cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER‐Mitochondrial Contacts

MedComm, Volume 6, Issue 10, October 2025.
cZFP609 mediates the cross‐talk between vasculature and cartilage. VSMC‐derived cZFP609 stabilizes the oligomeric form of BiP in chondrocytes, which suppresses TNFα‐induced ER stress signaling and abolishes aberrant ERMC remodeling, and thereby alleviates ferroptosis of chondrocytes and OA progression. ABSTRACT Vascular dysfunction is implicated in the
Yu Song, Jun‐Long Luo, Fan Zhang, Jie Shi, Shuai Du, Hai‐Bin Jiang, Wen‐Di Zhang, Si‐Ying Chen, Dan‐Dan Zhang, Peng Kong, Yuan Gao, Mei Han, Han Li   +12 more
wiley   +1 more source

Host-directed therapeutic targets in macrophages and their ligands against mycobacteria tuberculosis. [PDF]

Infect Immun
Li J, Wang Y, He L, Yang L, Tao T, Bai L, Luo Y.   +6 more
europepmc   +1 more source

Acute Myocardial Infarction: Molecular Pathogenesis, Diagnosis, and Clinical Management

MedComm, Volume 6, Issue 10, October 2025.
Key pathogenic mechanisms in AMI. Oxidative stress and mitochondrial dysfunction induce ROS accumulation, while DAMPs‐PRRs interaction triggers inflammatory cascades. Programmed cell death pathways and epigenetic regulation collectively constitute the core components of AMI pathogenesis.
Mengmeng Zhu, Yiwen Li, Qian Xu, Wenting Wang, Yanfei Liu, Yue Liu   +5 more
wiley   +1 more source