Results 351 to 360 of about 84,834 (402)

Deacetylation of BAP31 by sirtuin 2 attenuates apoptosis of hepatocytes induced by endoplasmic reticulum stress, in chronic alcoholic liver injury

British Journal of Pharmacology, Volume 182, Issue 20, Page 5023-5037, October 2025.
Abstract Background and Purpose Endoplasmic reticulum (ER) stress is a crucial pathogenic mechanism in alcoholic liver disease (ALD). B‐cell receptor‐associated protein 31 (BAP31) can regulate ER homeostasis and anti‐apoptosis, but the function and regulation of BAP31 in ALD are unclear.
Sai Wang, Yufeng Wang, Wen Shan, Guoyang Li, Ran Yan, Zhecheng Wang, Yan Zhao, Jihong Yao, Ning Zhang   +8 more
wiley   +1 more source

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway

Cell Proliferation, Volume 58, Issue 10, October 2025.
ECH protects senescent oocytes by stabilising the cytoskeleton, restoring mitochondrial function, reducing oxidative stress and maintaining cellular homeostasis, primarily through the GJA1/SIRT1 signalling pathway. ABSTRACT As maternal age increases, the decline in oocyte quality emerges as a critical factor contributing to reduced reproductive ...
Liuqing Yang, Xinle Lai, Fangxuan Lin, Nan Shi, Xinya Xu, Heng Wang, Xiaotian Li, Dan Shen, Haimo Qian, Xin Jin, Jiayi Chen, Zhongwei Huang, Xing Duan, Qin Zhang   +13 more
wiley   +1 more source

Obeticholic acid prevents cyclophosphamide-induced placental injury via SIRT1 and TLR4/NF-κB pathways. [PDF]

BMC Pharmacol Toxicol
Abdelzaher WY, Khalaf HM, Ahmed SM, Attya ME, Mohamed AA, Ali AMM, Gaber SS, Abdel-Hakeem AKA, Mohammed EM, Hassan M.   +9 more
europepmc   +1 more source

Alleviating the IL-1β-stimulated extracellular matrix degradation in osteoarthritis, and chondrocyte inflammation by <i>Morinda officinalis</i> polysaccharide via the SIRT6/NF-κB pathway. [PDF]

Biomol Biomed
Zhao D, Xing S, Qi J, Wei Z, Huang J, Sun J, Wen X, Wang Y.   +7 more
europepmc   +1 more source

Sirtuin 3 in diabetic kidney disease: mechanisms and pharmacotherapy. [PDF]

Ren Fail
Chen Y, Wang Y, Yu D, Zhao H, Li P.
europepmc   +1 more source

Sirtuins and Gut Microbiota: Dynamics in Health and a Journey from Metabolic Dysfunction to Hepatocellular Carcinoma. [PDF]

Cells
Zhra M, Elahi MA, Tariq A, Abu-Zaid A, Yaqinuddin A.   +4 more
europepmc   +1 more source

Molecular Mechanism of Antidepressant Effects of Active Ingredients in Traditional Chinese Medicine: The Role of Autophagy. [PDF]

Alpha Psychiatry
Zhang LJ, Chen D, Xu KY, Shang RR, Liu XY, Li ZF, Wang KF, Zhang M.   +7 more
europepmc   +1 more source

UEG Week 2025 Oral Presentations

United European Gastroenterology Journal, Volume 13, Issue S8, Page S7-S188, October 2025.
wiley   +1 more source

UEG Week 2025 Poster Presentations

United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source