Results 351 to 360 of about 87,529 (407)

Cellular Senescence, Inflammaging and Cardiovascular Disease

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders, Denada Arifaj, Julian U. G. Wagner, Stefanie Dimmeler   +3 more
wiley   +1 more source

Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes. [PDF]

Int J Mol Sci
Takemoto M, Sugishita Y, Takahashi-Suzuki Y, Fujiya H, Niki H, Yudoh K.   +5 more
europepmc   +1 more source

Trained Immunity and Cardiovascular Risk: An Immunological Perspective

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden, Jason Chai, Tafadzwa T. J. Kufazvinei, Robin P. Choudhury   +3 more
wiley   +1 more source

Role of human umbilical cord mesenchymal stem cells in diabetic kidney disease. [PDF]

World J Stem Cells
Liu Y, Shan XQ, Li YJ, Gao WL, Zhao L.
europepmc   +1 more source

Causal links between iron status, mitochondrial function, and laryngeal and hypopharyngeal cancers: a Mendelian study. [PDF]

Discov Oncol
Zhao J, Chen L, Han B, Li S, Zhang Y, Gao G, Liu J.   +6 more
europepmc   +1 more source

Correction: Yoon et al. Black Wheat Extracts (Arriheuk) Regulate Adipogenesis and Lipolysis via Adenosine Monophosphate (AMP) Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Signaling Pathways. <i>Foods</i> 2023, <i>12</i>, 2727. [PDF]

Foods
Yoon Y, Park MK, Kim KH, Lee GH.
europepmc   +1 more source

Mitochondrial Health Through Nicotinamide Riboside and Berberine: Shared Pathways and Therapeutic Potential. [PDF]

Int J Mol Sci
Visalli F, Capobianco M, Cappellani F, Rapisarda L, Spinello A, Avitabile A, Cannizzaro L, Gagliano C, Zeppieri M.   +8 more
europepmc   +1 more source

Filament formation and NAD processing by noncanonical human FAM118 sirtuins. [PDF]

Nat Struct Mol Biol
Baretić D, Missoury S, Patel K, Martinez M, Coste F, Zhu K, Smith R, Kopasz AG, Lu Y, Bigot N, Chapuis C, Riou R, Đukić N, Goffinont S, Pressoir V, Patačko S, Timinszky G, Delarue M, Castaing B, Ahel D, Mikoč A, Huet S, Ahel I, Suskiewicz MJ.   +23 more
europepmc   +1 more source

Sirtuins and tumor immunity: mechanistic insights, immunotherapy prospects, and therapeutic horizons. [PDF]

Front Immunol
Gu J, Liu S, Xiao W, Qu W.
europepmc   +1 more source