Results 231 to 240 of about 65,710 (330)

Sirtuin 1 (SIRT1); SIRT2 [PDF]

open access: yesScience-Business eXchange, 2014
openaire   +1 more source

Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang   +5 more
wiley   +1 more source

Retraction for Piracha et al., “Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway”

open access: diamond
Zahra Zahid Piracha   +8 more
openalex   +1 more source

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Genetic inactivation of the phosphatase activity of soluble epoxide hydrolase prevents the development of pulmonary hypertension in rats, partly through upregulation of SIRT3 expression and decreased cell proliferation and apoptosis‐related proteins. Targeting sEH‐P emerges as a promising therapeutic strategy for pulmonary hypertension.
Matthieu Leuillier   +17 more
wiley   +1 more source

Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation. [PDF]

open access: yesCardiovasc Res
Velagapudi S   +20 more
europepmc   +1 more source

DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu   +12 more
wiley   +1 more source

Functional and Nutraceutical Properties of Protein and Polyphenols Extracted From Agro‐Industrial Waste: A Comprehensive Review

open access: yeseFood, Volume 7, Issue 1, February 2026.
The article underscores the promising future perspectives of utilizing agro‐industrial waste, envisioning sustainable production processes, and meeting the increasing demand for environmentally friendly and health‐promoting products. ABSTRACT The growing imperative for increased food production has propelled an example alteration in the perception of ...
Fakhar Islam   +9 more
wiley   +1 more source

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