Results 231 to 240 of about 63,033 (309)

Sirtuin-1 Regulates Mitochondrial Calcium Uptake Through Mitochondrial Calcium Uptake 1 (MICU1). [PDF]

Life (Basel)
Zhang X, Liu S, Su Y, Zhang L, Guo T, Wang X.   +5 more
europepmc   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Surgical Residents Make Significant Contributions to Ongoing Cancer Research [PDF]

, 2009

core   +1 more source

The clinical value of serum sirtuin-1 concentration in the diagnosis of metabolic dysfunction-associated steatotic liver disease. [PDF]

BMC Gastroenterol
Amirkhizi F, Taghizadeh M, Khalese-Ranjbar B, Hamedi-Shahraki S, Asghari S.   +4 more
europepmc   +1 more source

H2O2‐Activated Serotonin Precursor Probe for Mapping Neuronal Redox Homeostasis Reveals 5‐HT Interactions with Neighboring Proteins Under Oxidative Stress

Advanced Science, Volume 12, Issue 39, October 20, 2025.
HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu, Jiwen Yuan, Tuanjie Zhang, Xinyi Cai, Meng Xu, Xueao Wang, Rui Wang, Bing Zhang, Hai‐Liang Zhu, Yong Qian   +9 more
wiley   +1 more source

Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness

, 2016
Jessica Fry, Leona Al Sayah, Robert M. Weisbrod, Isabelle Van Roy, Xiang Weng, Richard A. Cohen, Markus Bachschmid, Francesca Seta   +7 more
openalex   +1 more source

MicroRNA-124a/Sirtuin 1 pathway inhibits autophagy to promote hepatocyte apoptosis in acute-on-chronic liver failure. [PDF]

Mol Biol Rep
Xu H, Wang X, Wang Y, Shen C, Ma L, Zhao C.   +5 more
europepmc   +1 more source

Entwined processes in Alzheimer's disease: Brain cellular senescence and Alzheimer's disease pathology

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract Alzheimer's disease (AD) is one of the most common age‐related neurodegenerative diseases with severe progressive dementia. Amyloid beta (Aβ) deposition and phosphorylated tau accumulation are two typical AD pathologies, which could drive senescence in various types of brain cells.
Wen Li, Ying Han, Peichang Wang, Qiao Song   +3 more
wiley   +1 more source

Dapagliflozin and Sirtuin-1 interaction and mechanism for ameliorating atrial fibrillation in a streptozotocin-induced rodent diabetic model. [PDF]

Biomol Biomed
Lee WC, Lin YW, Shih JY, Chen ZC, Wu NC, Chang WT, Liu PY.   +6 more
europepmc   +1 more source

Ononin, a Natural Isoflavone Glycoside, Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Regulating Neuroinflammation and Oxidative Stress

Brain and Behavior, Volume 15, Issue 10, October 2025.
Ononin alleviates postoperative cognitive dysfunction in aged mice by regulating neuroinflammation and oxidative stress. ABSTRACT Objective Postoperative cognitive dysfunction (POCD) is a serious neurological complication that currently lacks effective clinical prevention and treatment.
Ming Li, Qingmei Peng, Min Zhu, Qilin Liu, Simin Yang, Cansheng Gong, Jingyan Lin, Qingbo Yu   +7 more
wiley   +1 more source