Results 241 to 250 of about 65,710 (330)

Surgical Residents Make Significant Contributions to Ongoing Cancer Research [PDF]

, 2009

core   +1 more source

Significant association of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) rs3846662 and sirtuin 1 (SIRT1) rs7895833 and apolipoprotein E (APOE) hypermethylation with mild cognitive impairment (MCI)

, 2019
Ting Zou, Yali Duan, Xiaohui Zhou, Wei Chen, Xiuru Ying, Guili Liu, Yongjie Zhao, Meisheng Zhu, Abuliz Pari, Kader Alimu, Haijun Miao, Keyim Kabinur, Lei Zhang, Qinwen Wang, Shiwei Duan   +14 more
openalex   +1 more source

Salvia coccinea and Apigenin: A Natural Treasure of Lamiaceae in Pharmacological Innovation

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Salvia coccinea is rich in bioactive phytochemicals, notably the flavonoid apigenin, offering strong antioxidant, anti‐inflammatory, and antimicrobial effects. By modulating inflammatory and oxidative pathways, it shows potential for managing chronic diseases.
Muhammad Usman Khalid, Muhammad Tauseef Sultan, Muhammad Maaz, Shehnshah Zafar, Anum Shoukat, Nudrat Khursheed, Matteo Bordiga, Amna Junaid   +7 more
wiley   +1 more source

Targeting sirtuin 1/nuclear factor erythroid 2-related factor 2/tumor necrosis factor-α pathway to modulate hepatic ischemia reperfusion-induced injury. [PDF]

World J Hepatol
Kelleni MT, Abdelzaher WY, Adly M, Attya ME, Fawzy MA, Ibrahim MA.   +5 more
europepmc   +1 more source

Sirtuin 1 and angiotensin II as inflammatory modulators in the development of diabetes [PDF]

, 2015
Constanze Thienel
openalex   +1 more source

Novel Roles for the Ectoenzyme CD38 in the Maintenance of Transcriptional and Metabolic Homeostasis in Astrocytes

Glia, Volume 74, Issue 2, February 2026.
CD38 deficiency influences brain NAD/NAM metabolism. Global CD38 deficiency drives changes in astrocyte mitochondrial, metabolic, senescence, and neurodegenerative‐related genes. CD38 deficiency alters glial reactivity and astrocyte bioenergetics. ABSTRACT CD38 is an ectoenzyme that converts NAD+ to NAM to help maintain bioenergetic homeostasis.
S. Basak, A. M. Colafrancesco, R. D. Hernandez, X. Wei, L. J. McMeekin, D. Dang, M. Simmons, J. L. Browning, K. Noel, F. Zhou, F. E. Lund, J. S. Saad, S. G. Watsen, A. M. Pickrell, R. M. Cowell, M. L. Olsen   +15 more
wiley   +1 more source

Correction: Berberine ameliorates subarachnoid hemorrhage injury via induction of Sirtuin 1 and inhibiting HMGB1/Nf-κB pathway. [PDF]

Front Pharmacol
Zhang XH, Peng L, Zhang J, Dong YP, Wang CJ, Liu C, Xia DY, Zhang XS.   +7 more
europepmc   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 3, Page 475-487, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao, Junjie Cheng, Yiming Zheng, Jing Wu, Jia Fan, Haixiang Sun, Chao Gao   +6 more
wiley   +1 more source

Impact of sirtuin‑1 expression on progression‑free survival in non‑endometrioid endometrial cancer: A retrospective cohort study. [PDF]

Oncol Lett
Yalcin N, Yildirim HT, Alci A, Gokkaya M, Goksu M, Ureyen I, Toptas T.   +6 more
europepmc   +1 more source

Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease

, 2013
Xia Zhou, Lucy X. Fan, William E. Sweeney, John M. Denu, Ellis D. Avner, Xiaogang Li   +5 more
openalex   +1 more source