Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.ABSTRACT Background Sarcopenia has become an urgent socioeconomic problem in rapidly aging societies. The pathogenesis of age‐associated sarcopenia is not fully understood and no effective therapeutic strategies have been developed to date. Recent studies have suggested the importance of the functional linkage between the brain and skeletal muscles in ...
Takahiro Eguchi +2 more
wiley +1 more source
MicroRNA-378b regulates α-1-type 1 collagen expression via sirtuin 6 interference
, 2017 Da-Hye Joo +7 more
openalex +2 more sources
Sirtuin 1 in regulating the p53/glutathione peroxidase 4/gasdermin D axis in acute liver failure. [PDF]
World J GastroenterolKatoch S, Patial V.
europepmc +1 more source
Enhancing Muscle Quality: Exploring Leucine and Whey Protein in Sarcopenic Individuals
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.ABSTRACT Background Sarcopenia is characterised by a decline in the skeletal muscle mass with increasing age. This poses many challenges to the health and independence of older individuals. New and emerging studies have focused on supplementing leucine‐enriched whey protein and resistance training in older adults to mitigate the effects of sarcopenia ...
Aiman Ijaz +8 more
wiley +1 more source
A role for sirtuin 1 in FGF23 activation following β-glycerophosphate treatment. [PDF]
Pflugers ArchRatsma DMA +4 more
europepmc +1 more source
Engineering Efferocytosis for Bone Regeneration
Macromolecular Bioscience, Volume 25, Issue 10, October 2025.The repair of bone tissue in acute and chronic injuries is a significant long‐standing clinical challenge. Biomaterials‐based interventions are well‐positioned to interrogate mechanisms of efferocytosis due to their ability to provide support and guide cellular activity.
Jacob Miszuk, Linna Zhong, Hongli Sun
wiley +1 more source
Correction: Yoon et al. Black Wheat Extracts (Arriheuk) Regulate Adipogenesis and Lipolysis via Adenosine Monophosphate (AMP) Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Signaling Pathways. <i>Foods</i> 2023, <i>12</i>, 2727. [PDF]
FoodsYoon Y, Park MK, Kim KH, Lee GH.
europepmc +1 more source
Free Radicals in Health and Disease
MedComm, Volume 6, Issue 10, October 2025.Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley +1 more source
The effect of weight loss therapies on sirtuin 1 regulation: a systematic review and meta-analysis of randomized controlled trials. [PDF]
BMC NutrSohouli MH +4 more
europepmc +1 more source
MedComm, Volume 6, Issue 10, October 2025.cZFP609 mediates the cross‐talk between vasculature and cartilage. VSMC‐derived cZFP609 stabilizes the oligomeric form of BiP in chondrocytes, which suppresses TNFα‐induced ER stress signaling and abolishes aberrant ERMC remodeling, and thereby alleviates ferroptosis of chondrocytes and OA progression. ABSTRACT Vascular dysfunction is implicated in the
Yu Song +12 more
wiley +1 more source