How to halve ploidy : lessons from budding yeast meiosis [PDF]
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash +2 more
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Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion [PDF]
Genome stability involves accurate replication and DNA repair. Broken replication forks, such as those encountering a nick, lead to double strand breaks (DSBs), which are preferentially repaired by sister-chromatid recombination (SCR).
Aguilera López, Andrés +2 more
core +1 more source
Beside partial coverage in three reviews so far (1994, 2009, 2019), there is no review on genotoxic studies dealing with mercury (Hg) and human exposure using the most usual genotoxic assays: sister chromatid exchanges (SCE), chromosomal aberrations (CA),
Juana Sánchez-Alarcón +5 more
doaj +1 more source
Smoking and sister chromatid exchange [PDF]
The present survey comprises analysis of sister chromatid exchange (SCE) frequencies in the peripheral blood lymphocytes of 100 subjects: 83 healthy men and women, both cigarette smokers and nonsmokers and 17 children. Both for men (30 smoking, 22 nonsmoking) and for women (13 smoking, 18 nonsmoking) the frequency of SCEs is significantly higher among ...
K, Husgafvel-Pursiainen +3 more
openaire +2 more sources
Study of the Effect of MMC on the Sister Chromatid Exchange in the Human Lymphocytes [PDF]
Some environmental mutagenic agents cause genomic instability and increase susceptibility of DNA damage. One of them is mitomycin C which is connected to DNA as an alkylating factor and affects susceptible cells to reduction reactions.
S ِAkbari-Kamranvar +2 more
doaj
The cohesion protein SOLO associates with SMC1 and is required for synapsis, recombination, homolog bias and cohesion and pairing of centromeres in Drosophila Meiosis. [PDF]
Cohesion between sister chromatids is mediated by cohesin and is essential for proper meiotic segregation of both sister chromatids and homologs. solo encodes a Drosophila meiosis-specific cohesion protein with no apparent sequence homology to cohesins ...
Rihui Yan, Bruce D McKee
doaj +1 more source
The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time [PDF]
Peer ...
Andrulis ED +51 more
core +2 more sources
Lack of clastogenic effects of L-thyroxine in whole-blood cultured human lymphocytes
Thyroid hormones stimulate aerobic metabolism which may lead to oxidative stress accompanied by damage to various cellular macromolecules, including DNA.
Ninoslav Djelic +6 more
doaj +1 more source
Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad +102 more
core +2 more sources
Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +2 more sources

