Results 11 to 20 of about 22,194 (215)

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta-Analysis. [PDF]

J Appl Toxicol
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Pinto TG, do Nascimento VF, Guerra GAH, Takeshita WM, Sales RA, de Moraes Malinverni AC, Guimaraes LL, Ribeiro DA.   +7 more
europepmc   +2 more sources

Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

Nature Communications, 2021
Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromatid ...
Rohit Prakash, Thomas Sandoval, Florian Morati, Jennifer A. Zagelbaum, Pei-Xin Lim, Travis White, Brett Taylor, Raymond Wang, Emilie C. B. Desclos, Meghan R. Sullivan, Hayley L. Rein, Kara A. Bernstein, Przemek M. Krawczyk, Jean Gautier, Mauro Modesti, Fabio Vanoli, Maria Jasin   +16 more
doaj   +1 more source

Assessment of the genotoxic potential of temephos [PDF]

Pesticidi i Fitomedicina, 2020
Genotoxic effects of pesticides are of great concern for public health due to the fact that they are widely used for both domestic and industrial purposes.
Cobanoglu Hayal, Cayir Akin
doaj   +1 more source

Evaluation of Sister Chromatid Exchanges and Hypoxanthine guanine phosphoribosyl transferase Gene Mutation Assay in Peripheral Lymphocytes of Workers Exposed to Radiation at Al-Tuwaitha Site

The Iraqi Journal of Veterinary Medicine, 2015
The present study aims at using the biological techniques in a genotoxicity assessment of low doses of radiation in samples of workers in Al-Tuwaitha site due to decommissioning to radioactive contamination as a result of work.
Abdulsahib K. Ali
doaj   +1 more source

Genotoxic effects of copper sulfate in rabbits [PDF]

Archives of Biological Sciences, 2013
This study was carried out to determine the genotoxic effects of oral application of CuSO4 in rabbits by the chromosome aberration (CA) and sister chromatid exchange (SCE) tests.
Georgieva S., Popov B., Petrov V.
doaj   +1 more source

Analysis of De Novo HOXA 13 Polyalanine Expansions Supports Replication Slippage Without Repair in Their Generation [PDF]

, 2013
Polyalanine repeat expansion diseases are hypothesized to result from unequal chromosomal recombination, yet mechanistic studies are lacking. We identified two de novo cases of hand‐foot‐genital syndrome (HFGS) associated with polyalanine expansions in ...
Innis, Jeffrey W., Keegan, Catherine E., Larsen, Christine A., Lefebvre, Nanci, Owens, Kailey M., Quinonez, Shane C., Roulston, Diane, Stadler, H. Scott, Thomas, Peedikayil E.   +8 more
core   +1 more source

"Sister Chromatid Exchanges and Micronuclei in Lymphocyte of Nurses Handling Antineoplastic Drugs" [PDF]

Iranian Journal of Public Health, 2001
Individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. The effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different ...
M Ansari-Lari, M Saadat, M Shahryari, DD Farhud   +3 more
doaj   +1 more source

iPSC line derived from a Bloom syndrome patient retains an increased disease-specific sister-chromatid exchange activity.

Stem Cell Research, 2020
Bloom syndrome is characterized by severe pre- and postnatal growth deficiency, immune abnormalities, sensitivity to sunlight, insulin resistance, and a high risk for many cancers that occur at an early age. The diagnosis is established on characteristic
Vincent Gatinois, Romain Desprat, Fabienne Becker, Lydiane Pichard, Florence Bernex, Bertrand Isidor, Franck Pellestor, Jean-Marc Lemaitre   +7 more
doaj   +1 more source

Sister-chromatid exchange in 4 human races [PDF]

, 1981
The frequencies of sister-chromatid exchanges (SCE) were investigated in lymphocytes in 32 normal adult individuals of both sexes with no interracial familial backgrounds from Caucasian, American black, oriental and native American races.
Butler, Merlin G.
core   +1 more source

Smc5/6: a link between DNA repair and unidirectional replication? [PDF]

, 2008
Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada, Antony M. Carr, AR Lehmann, B Hu, D Branzei, D Ivanov, DM Sheedy, E Ampatzidou, E Unal, E Unal, EA Andrews, ES Chen, F Onoda, G De Piccoli, GJ Cost, H Morikawa, HB Lindroos, HM Verkade, I Miyabe, J Palecek, J Rouse, J Sergeant, J Torres-Rosell, J Torres-Rosell, JK Chin, Johanne M. Murray, KL Borden, KM Lee, L Strom, L Strom, MI Fousteri, MN Boddy, N Aono, PR Potts, PR Potts, PR Potts, S Pebernard, S Pebernard, SH Harvey, T de Lange, T Kobayashi, T Mengiste, T Morishita, TM Roberts, WH McDonald, WM Thorburn, X Zhao   +46 more
core   +1 more source