Results 21 to 30 of about 22,194 (215)

High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast. [PDF]

, 2017
In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule.
Dominska, Margaret, Petes, Thomas D, Yim, Eunice, Yin, Yi   +3 more
core   +3 more sources

Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae. [PDF]

, 2013
In the yeast Saccharomyces cerevisiae and most other eukaryotes, mitotic recombination is important for the repair of double-stranded DNA breaks (DSBs). Mitotic recombination between homologous chromosomes can result in loss of heterozygosity (LOH).
Petes, Thomas D, Yin, Yi
core   +1 more source

Are there any genotoxic effects of laser epilation applications on human? An observational study

National Journal of Physiology, Pharmacy and Pharmacology, 2014
Background: Laser epilation is a method of removal of unwanted hair from the body and its use for this cosmetic purpose is gaining increasing popularity.
Zeynep Ocak, Tulay Ozlu, Sener Tasdemir, Handan Bilen, Ertuğrul Mevlut Kocaman   +4 more
doaj   +1 more source

Vitamin B12 protects against DNA damage induced by hydrochlorothiazide

Saudi Pharmaceutical Journal, 2018
DNA damage induced by hydrochlorothiazide was previously reported in cultured human lymphocytes. In this study, we aimed to investigate the harmful effects of hydrochlorothiazide on DNA by measuring the spontaneous frequency of sister chromatid exchanges
Karem H. Alzoubi, Erva Bayraktar, Omar Khabour, Sayer I. Al-Azzam   +3 more
doaj   +1 more source

Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients [PDF]

, 2012
© 2012 Joksic et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium ...
Guc-Scekic, M, Joksic, G, Joksic, I, Leskovac, A, Ojani, M, Petrovic, S, Slijepcevic, P, Stankovic, A, Surralles, J, Trujillo, JP, Vujic, D, Zivkovic, M   +11 more
core   +3 more sources

The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

BMC Cell Biology, 2001
Background Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability.
Noonan James P, Yankiwski Victor, Neff Norma F   +2 more
doaj   +1 more source

Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex? [PDF]

, 2013
This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.Peer ...
Donaldson, Anne D, Kubota, Takashi, Myung, Jae-Kyung   +2 more
core   +1 more source

Chromosome segregation in plant meiosis [PDF]

, 2014
Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico, Geelen, Danny, Pawlowski, Wojtek, Tiang, Choon Lin, Zamariola, Linda   +4 more
core   +2 more sources

Meiotic DNA exchanges in C. elegans are promoted by proximity to the synaptonemal complex

Life Science Alliance, 2023
Exchanges between DNA molecules during meiosis are tightly controlled. This work shows that the synaptonemal complex is instrumental in regulating meiotic exchanges both between the parental chromosomes and between the sister chromatids.
David E Almanzar, Spencer G Gordon, Chloe Bristow, Antonia Hamrick, Lexy von Diezmann, Hanwenheng Liu, Ofer Rog   +6 more
doaj   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources