Study of the Effect of MMC on the Sister Chromatid Exchange in the Human Lymphocytes [PDF]
Journal of Kerman University of Medical Sciences, 2004 Some environmental mutagenic agents cause genomic instability and increase susceptibility of DNA damage. One of them is mitomycin C which is connected to DNA as an alkylating factor and affects susceptible cells to reduction reactions.
S ِAkbari-Kamranvar +2 more
doaj
The cohesion protein SOLO associates with SMC1 and is required for synapsis, recombination, homolog bias and cohesion and pairing of centromeres in Drosophila Meiosis. [PDF]
PLoS Genetics, 2013 Cohesion between sister chromatids is mediated by cohesin and is essential for proper meiotic segregation of both sister chromatids and homologs. solo encodes a Drosophila meiosis-specific cohesion protein with no apparent sequence homology to cohesins ...
Rihui Yan, Bruce D McKee
doaj +1 more source
SISTER CHROMATID EXCHANGES IN PHOTOCHEMOTHERAPY
Journal of Investigative Dermatology, 1977 Sister chromatid exchanges (SCE), presently considered highly sensitive indicators for chromosomal effects of potential mutagens and carcinogens in mammalian cells, were studied in circulating white blood cells from patients with widespread psoriasis who were being treated with 8-methoxy-psoralen and long-wavelength ultraviolet light (UVA) photo ...
Wolff-Schreiner, Elisabeth C. +3 more
openaire +2 more sources
Toxics, 2021 Beside partial coverage in three reviews so far (1994, 2009, 2019), there is no review on genotoxic studies dealing with mercury (Hg) and human exposure using the most usual genotoxic assays: sister chromatid exchanges (SCE), chromosomal aberrations (CA),
Juana Sánchez-Alarcón +5 more
doaj +1 more source
The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. [PDF]
, 2018 Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability in the absence of the replication fork/replication ...
Branzei, Dana +5 more
core +2 more sources
Lack of clastogenic effects of L-thyroxine in whole-blood cultured human lymphocytes
Genetics and Molecular Biology, 2007 Thyroid hormones stimulate aerobic metabolism which may lead to oxidative stress accompanied by damage to various cellular macromolecules, including DNA.
Ninoslav Djelic +6 more
doaj +1 more source
No increase in radiation-induced chromosome aberration complexity detected by m-FISH after culture in the presence of 5’-bromodeoxyuridine [PDF]
, 2006 The thymidine analogue, 5’-bromodeoxyuridine (BrdU), is a known mutagen that is routinely introduced into culture media for subsequent Harlequin stain analysis and determination of cell cycle status.
Anderson +38 more
core +1 more source
Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe [PDF]
, 2006 Peer ...
Estreicher, A. +3 more
core +1 more source
Evaluation of Fish Micronucleus Results in Turkish Ecogenotoxicological Studies
Çanakkale Onsekiz Mart University Journal of Marine Sciences and Fisheries, 2020 In recent years, ecotoxicological studies have been conducted around the world, especially in aquatic ecosystems. It is noteworthy that genotoxicity tests have been frequently used in the biomonitoring of pollution.
Gülşen GÖNEY , Cengiz GAZELOĞLU
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On a break with the X: the role of repair of double-stranded DNA breaks in X-linked disease [PDF]
, 2012 The problem of managing free reactive DNA ends in eukaryotic cells has resulted in the development of a number of mechanisms in order to ensure that free ends are rendered non-reactive, or that the double-strand DNA breaks generating the free ends are ...
Cecceroni, Lucia +2 more
core +4 more sources