Rad54: the Swiss Army knife of homologous recombination? [PDF]
, 2006 Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich +3 more
core +2 more sources
Evaluation of Fish Micronucleus Results in Turkish Ecogenotoxicological Studies
Çanakkale Onsekiz Mart University Journal of Marine Sciences and Fisheries, 2020 In recent years, ecotoxicological studies have been conducted around the world, especially in aquatic ecosystems. It is noteworthy that genotoxicity tests have been frequently used in the biomonitoring of pollution.
Gülşen GÖNEY , Cengiz GAZELOĞLU
doaj +1 more source
Chromosome fragility in Freemartin cattle
Italian Journal of Animal Science, 2010 The aim of the present study was to verify chromosome fragility in freemartin cattle using chromosome aberration (CA) and sister chromatid exchange (SCE) tests. A total of eighteen co-twins were investigated.
V. Barbieri +7 more
doaj +1 more source
DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells. [PDF]
, 2013 Asymmetry of cell fate is one fundamental property of stem cells, in which one daughter cell self-renews, whereas the other differentiates. Evidence of nonrandom template segregation (NRTS) of chromosomes during asymmetric cell divisions in ...
Chen, Robert +6 more
core +2 more sources
Evulation of Antimutagenic Activity of Ni(II) Complexes with Unsymmetric Schiff Bases
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2020 In this work, Ni(II) complexes with unsymmetricSchiff bases (NiL1, NiL2, NiL3, NiL4)wereprepared by a two-stage method reported by one of us recently forinvestigate antimutagenic properties.
Hamit Emre Kızıl +4 more
doaj +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Comparison of genome stability in two pig breeds by using the sister chromatid exchange (SCE) test
Italian Journal of Animal Science, 2010 The sister chromatid exchange (SCE) test has been used to detect genome stability in humans (Chaganti, 1974) and the main livestock species (Ciotola et al., 2004; Di Meo et al., 2000; Di Berardino et al., 1979), and to discover DNA damage caused by a ...
V. Barbieri +5 more
doaj +1 more source
Mouse RAD54 affects DNA double-strand break repair and sister chromatid exchange [PDF]
, 2000 Cells can achieve error-free repair of DNA double-strand breaks (DSBs) by homologous recombination through gene conversion with or without crossover.
Beverloo, H.B. (Berna) +5 more
core
Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time [PDF]
, 2003 DNA single strand breaks (SSBs) are one of the most frequent DNA lesions in genomic DNA generated either by oxidative stress or during the base excision repair pathways.
Asakura, Shoji +5 more
core +3 more sources
Cell Proliferation, EarlyView.Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source