Results 101 to 110 of about 15,404 (212)
Frontiers in EndocrinologyBackgroundMicroRNAs (miRNAs) and their target genes can elucidate mechanisms of drug action and serve as potential therapeutic biomarkers.MethodsTo evaluate the effects of bedtime NPH insulin and sitagliptin on serum miRNA expression in individuals with ...
Aritania Sousa Santos +3 more
doaj +1 more source
Nickel Photocatalytic Access to β‐Arylated β‐Amino Acids
Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.Converting naturally abundant amino acids to non‐canonical derivatives in one step under mild conditions allows for improved pharmaceutical properties. Now, this is achieved for β‐arylated β‐amino acids, which are available in good yields directly from aspartic acid, and have the potential to become platform chemicals for drug discovery.
Tim S. Stamp +3 more
wiley +1 more source
Sitagliptin as combination therapy in the treatment of type 2 diabetes mellitus
, 2009 Shannon A Miller1, Erin L St Onge2, J Roger Accardi31Pharmacotherapy Faculty, Florida Hospital East Family Practice Residency, Orlando, Florida, USA; 2University of Florida College of Pharmacy, Orlando Campus, Florida, USA; 3Accardi Clinical Pharmacy ...
Erin L St Onge +2 more
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Rosuvastatin-Induced Rhabdomyolysis as a Result of Drug Interaction With Sitagliptin: A Case Report
Clinical Medicine Insights: Case ReportsRhabdomyolysis was not reported in clinical trials with Sitagliptin alone. However, several reports in the literature on rhabdomyolysis resulted from the interaction between statins and Sitagliptin. In patients with type 2 diabetes and hyperlipidemia, it
Abdolamir Atapour +3 more
doaj +1 more source
Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals
Mediators of Inflammation, 2014 This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of type 2 diabetes mellitus; the Zucker diabetic fatty (ZDF) rat ...
Catarina Marques +8 more
doaj +1 more source
Sitagliptin and Simvastatin Interaction Causing Rhabdomyolysis and AKI
, 2019 We report a case of rhabdomyolysis and severe acute kidney injury (AKI) requiring dialysis in a 69-year-old male who was recently started on sitagliptin while on chronic simvastatin therapy.
Yousef Hattab +3 more
core +1 more source
, 2011 Sitagliptin is a newer oral hypoglycemic drug of the dipeptidyl peptidase-IV inhibitor class. It appears to be a promising newer oral hypoglycemic agent.
Shivashankara, K. N. +3 more
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Sitagliptin: New Oral Antidiabetic Agent for Tip 2 Diabetes Mellitus [PDF]
, 2011 Tip 2 Diyabet (T2DM) dünya genelinde yaygın ve hastalar hatta toplum için önemli sonuçları olan bir epidemik bir hastalıktır. T2DM için mevcut tedavi yöntemlerinin doza bağlı sınırlamaları ve yan etkileri (kilo artışı, hipoglisemi ve sindirim sistemi ...
Hazman, Ömer
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Sitagliptin accelerates restoration of normal blood glucose levels.
, 2013 (A) C57Bl6 mice were treated with a single dose of streptozotocin (180 mg/kg) and placed on either a normal chow diet or diet containing 5.5% sitagliptin following syngeneic islet transplantation (day 0).
Neelam Lingwal (183259) +5 more
core +1 more source
, 2019 Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
PALANISAMY, KAMARAJ +2 more
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