Results 101 to 110 of about 23,280 (257)
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
SITAGLIPTIN- A COMPREHENSIVE REVIEW
, 2023 Sitagliptin is an orally administered, potent, and highly selective inhibitor of dipeptidyl peptidase-4 (DPP-4) and was the first agent of its class to be approved for use in the management of adults with type 2 diabetes.
Pavankumar Wankhade*, Shraddha Suryawanshi, Deepti Waghmare
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Evaluation of Anticancer Activity of Sitagliptin against Hepatocellular Carcinoma: An In Vitro Study
Medical Journal of BabylonBackground: Hepatocellular carcinoma is a malignant liver tumor constituting greater than 90% of liver primary tumors. Most of chemotherapeutic drugs used nowadays are cytotoxic, which rise the necessity to find newer agents with anticancer activity and ...
Ruqaya A. Ameen +2 more
doaj +1 more source
Food Safety and Health, EarlyView.Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid +8 more
wiley +1 more source
Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis
VIEW, EarlyView.In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian +5 more
wiley +1 more source
Impact of Sitagliptin on Inflammatory Biomarkers in Type 2 Diabetes Mellitus [PDF]
Background: Type 2 diabetes mellitus (T2DM) is associated with low-grade inflammatory response, which was reported to contribute to insulin resistance. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is widely used for glycemic control and has ...
Aqeel Meer AL-ZAMILY
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Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng +5 more
wiley +1 more source
A review of sitagliptin with special emphasis on its use in moderate to severe renal impairment [PDF]
, 2013 Vinay S Eligar,1 Stephen C Bain2 1University Hospital of Wales, Cardiff, UK; 2Singleton Hospital, Swansea University, Swansea, UK Abstract: Sitagliptin is the first dipeptidylpeptidase-4 inhibitor to be used in the management of type 2 diabetes.
Bain SC, Eligar VS
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Andrology, EarlyView.ABSTRACT Background Drugs used for diabetes and obesity increasingly shape male sexual and reproductive counseling, but clinical studies, trial registrations, regulatory labels, and patents answer different questions. Objectives The objective is to map these sources and define what each can support when counseling men receiving metabolic drugs ...
Marek Broul +3 more
wiley +1 more source
, 2023 Yuming Wang,1,2,* Yunting Zhou,2,* Xiao Zhou,2,* Xiaofei Su,2,* Xiaohua Xu,2 Huiqin Li,2 Jianhua Ma2 1Department of Geriatrics, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008 ...
Li H +6 more
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