Results 111 to 120 of about 23,280 (257)
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Sitagliptin improves insulin production.
, 2013 (A) Insulin content of islet grafts transplanted to the kidney capsule given asµg insulin per g kidney. Control = normal chow, Sitagliptin = 5.5% sitagliptin included into the rodent chow (p < 0.05; n = 6). (B) Insulin area (μm2) of sections of mouse
Neelam Lingwal (183259) +5 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Gastric inhibitory polypeptide (GIP)/Glucagon‐like peptide‐1 (GLP‐1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a sarcopenia component, this article summarizes emerging ...
Konstantinos Prokopidis
wiley +1 more source
Sitagliptin induced splenic infarcts [PDF]
, 2018 Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. DPP-4 inhibitors are remarkably well tolerated oral antihyperglycemic drugs with an adverse effect profile similar to that of placebo.
Bashir, Mir Iftikhar; Department of Endocrinology, Sher-i-Kashmir Institute of Medical Scences, Srinagar, Kashmir, India +3 more
core +1 more source
ENANTIOMETRIC SEPARATION OF SITAGLIPTIN IN A FIXED DOSE COMBINATION FORMULA OF SITAGLIPTIN AND METFORMIN BY A CHIRAL LIQUID CHROMATOGRAPHIC METHOD [PDF]
, 2019 Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
PALANISAMY, KAMARAJ +2 more
core +1 more source
Advancement of science, 2020 As a chronic inflammatory disease, diabetes mellitus creates a proinflammatory microenvironment around implants, resulting in a high rate of implant loosening or failure in osteological therapies.
Geng Xiang +8 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon +14 more
wiley +1 more source
EBioMedicine, 2020 Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Shreeya Tewary +13 more
doaj +1 more source
Effects of GLP‐1 agonists on the gut microbiota in type 2 diabetes mellitus: a systematic review
The FEBS Journal, EarlyView.This systematic review evaluated 17 studies (12 preclinical and five clinical) on GLP‐1 receptor agonists in type 2 diabetes, demonstrating effects on the gut microbiota and metabolic improvement. The studies showed an increase in Bacteroidetes, Lactobacillus, and Akkermansia, and a reduction in Firmicutes.
Ranicleide Santos Dantas +11 more
wiley +1 more source
, 2010 Sitagliptin is a newer oral hypoglycemic drug of the dipeptidyl peptidase-IV inhibitor class. It appears to be a promising newer oral hypoglycemic agent.
Weena Stanley +7 more
core +1 more source