Formulation and evaluation of sitagliptin phosphate and metformin hydrochloride trilayered tablets [PDF]
Sitagliptin phosphate when used alone is an oral anti hyperglycemic drug of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It is available as tablets under trade name JANUVIA.
Chaitanya.N, Prathima Srinivas M
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Review of sitagliptin phosphate: a novel treatment for type 2 diabetes
Baptist GallwitzDept. Medicine IV, Eberhard Karls University, Tuebingen, GermanyAbstract: Sitagliptin (Januvia®, Merck Pharmaceuticals) is a dipeptidyl-peptidase inhibitor (DPP-4 inhibitor) that has recently been approved for the therapy of type 2 ...
Baptist Gallwitz
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Method Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form [PDF]
Method Development and Validation of RP-HPLC for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form was developed using Qualisil C18 BDS Column(150×4.5mm,5µ) as stationary phase and Potassium dihydrogen phosphate and Acetonitrile in a ratio 60:
N. Gayathri, K. Prabhakaran, A. Naveen, M. Kavinilavu, S. Maheshboopathi, M. Manikandan, M. Kaviyarasu, N. Astalakshmi, M. Surendrakumar
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A simple and accurate reverse phase high performance liquid chromatography (RP-HPLC) method for the validative determination of assay and dissolution of Sitagliptin Phosphate Monohydrate 100mg was developed and validated as per USP 1225 and ICH ...
Inturi Venkatesh Chowdary +3 more
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Sitagliptin acting as Anti-Diabetic agent (Dipeptidyl peptidase-4 inhibitor) which boosts post prandial insulin release decreases Glucagon secretion and lower mean time as well as fasting blood glucose in type 2 diabetes mellitus. There is a strong rationale for combining a DPP-4i and a SGLT2i in patients with T2D because the two drugs exert different ...
openaire +1 more source
Spray-Dried Monocalcium Phosphate Monohydrate for Soluble Phosphate Fertilizer
International audienceMonocalcium phosphate monohydrate (MCPM) was obtained by water extraction of triple superphosphate. The solubility of MCPM is 783.1 g/L, and is entirely soluble.
Fiallo, Marina +4 more
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Titanium-containing bioactive phosphate glasses [PDF]
The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable ...
Knowles, Jonathan C. +18 more
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Hypoglycemia associated with off-label sitagliptin use
Heather P Whitley1,2, Kristi Kelley11Department of Pharmacy Practice, Auburn University Harrison School of Pharmacy, Auburn, AL, USA; 2Department of Community and Rural Medicine, University of Alabama School of Medicine, Tuscaloosa, AL, USAPurpose: To ...
Heather P Whitley, Kristi Kelley
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Formulation Development and In-Vivo, In- Vitro Evaluation of Sitagliptin Phosphate Floating Microspheres [PDF]
The purpose of the present investigation was the development and characterization of gastro-retentive floating drug delivery system for anti-diabetic drug Sitagliptin Phosphate that would retain the drug in stomach and continuously release the drug in ...
Aftab Alam, S. Rajasekaran
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ENANTIOMETRIC SEPARATION OF SITAGLIPTIN IN A FIXED DOSE COMBINATION FORMULA OF SITAGLIPTIN AND METFORMIN BY A CHIRAL LIQUID CHROMATOGRAPHIC METHOD [PDF]
Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
PALANISAMY, KAMARAJ +2 more
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