Results 31 to 40 of about 383,013 (128)

Formulation and evaluation of sitagliptin phosphate and metformin hydrochloride trilayered tablets [PDF]

open access: yes, 2013
Sitagliptin phosphate when used alone is an oral anti hyperglycemic drug of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It is available as tablets under trade name JANUVIA.
Chaitanya.N, Prathima Srinivas M
core   +2 more sources

Review of sitagliptin phosphate: a novel treatment for type 2 diabetes

open access: yes, 2007
Baptist GallwitzDept. Medicine IV, Eberhard Karls University, Tuebingen, GermanyAbstract: Sitagliptin (Januvia®, Merck Pharmaceuticals) is a dipeptidyl-peptidase inhibitor (DPP-4 inhibitor) that has recently been approved for the therapy of type 2 ...
Baptist Gallwitz
core  

Method Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form [PDF]

open access: yes
Method Development and Validation of RP-HPLC for the Estimation of Sitagliptin Phosphate in Tablet Dosage Form was developed using Qualisil C18 BDS Column(150×4.5mm,5µ) as stationary phase and Potassium dihydrogen phosphate and Acetonitrile in a ratio 60:
N. Gayathri, K. Prabhakaran, A. Naveen, M. Kavinilavu, S. Maheshboopathi, M. Manikandan, M. Kaviyarasu, N. Astalakshmi, M. Surendrakumar
core   +1 more source

Research Journal of Pharmaceutical, Biological and Chemical Sciences Development and Validation of RP-HPLC Method for Content Analysis and Dissolution Studies Of Sitagliptin Phosphate Monohydratein Pharmaceutical Dosage Forms

open access: yes, 2020
A simple and accurate reverse phase high performance liquid chromatography (RP-HPLC) method for the validative determination of assay and dissolution of Sitagliptin Phosphate Monohydrate 100mg was developed and validated as per USP 1225 and ICH ...
Inturi Venkatesh Chowdary   +3 more
core  

Review Of the Combination Dosage Form of Sitagliptin Phosphate Monohydrate and Dapagliflozin Propanediol Monohydrate as an Anti-Diabetic Agent

open access: yes
Sitagliptin acting as Anti-Diabetic agent (Dipeptidyl peptidase-4 inhibitor) which boosts post prandial insulin release decreases Glucagon secretion and lower mean time as well as fasting blood glucose in type 2 diabetes mellitus. There is a strong rationale for combining a DPP-4i and a SGLT2i in patients with T2D because the two drugs exert different ...
openaire   +1 more source

Spray-Dried Monocalcium Phosphate Monohydrate for Soluble Phosphate Fertilizer

open access: yes, 2015
International audienceMonocalcium phosphate monohydrate (MCPM) was obtained by water extraction of triple superphosphate. The solubility of MCPM is 783.1 g/L, and is entirely soluble.
Fiallo, Marina   +4 more
core   +1 more source

Titanium-containing bioactive phosphate glasses [PDF]

open access: yes, 2012
The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable ...
Knowles, Jonathan C.   +18 more
core   +1 more source

Hypoglycemia associated with off-label sitagliptin use

open access: yes, 2008
Heather P Whitley1,2, Kristi Kelley11Department of Pharmacy Practice, Auburn University Harrison School of Pharmacy, Auburn, AL, USA; 2Department of Community and Rural Medicine, University of Alabama School of Medicine, Tuscaloosa, AL, USAPurpose: To ...
Heather P Whitley, Kristi Kelley
core  

Formulation Development and In-Vivo, In- Vitro Evaluation of Sitagliptin Phosphate Floating Microspheres [PDF]

open access: yes
The purpose of the present investigation was the development and characterization of gastro-retentive floating drug delivery system for anti-diabetic drug Sitagliptin Phosphate that would retain the drug in stomach and continuously release the drug in ...
Aftab Alam, S. Rajasekaran
core   +1 more source

ENANTIOMETRIC SEPARATION OF SITAGLIPTIN IN A FIXED DOSE COMBINATION FORMULA OF SITAGLIPTIN AND METFORMIN BY A CHIRAL LIQUID CHROMATOGRAPHIC METHOD [PDF]

open access: yes, 2019
Objective: Sitagliptin phosphate and metformin hydrochloride tablet is an FDA approved combination product for the treatment of diabetes mellitus type 2. There are no reported evidence for estimation of undesired (S)-sitagliptin in a combination product.
PALANISAMY, KAMARAJ   +2 more
core   +1 more source

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